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  • Ivette Sandoval, PhD

    Ivette Sandoval, PhD, is an associate professor in the Department of Neurobiology at Barrow Neurological Institute.

    Dr. Sandoval’s expertise includes the application of gene therapy and gene editing techniques to the nervous system. She is a member of the American Society for Gene & Cell Therapy, The American Society for Neural Therapy and Repair, and the Society for Neuroscience.

    Dr. Sandoval earned her doctorate degree in biochemistry and molecular biology from Baylor College of Medicine in Houston. She also completed a postdoctoral fellowship in the Translational Science and Molecular Medicine Department at Michigan State University in East Lansing.

    Dr. Sandoval’s research interests include the use of gene editing tools and viral vectors to better understand and potentially treat neurodegenerative diseases. She also studies the etiology of Parkinson’s disease—specifically how aging and the alpha-synuclein protein affect epigenetic mechanisms of midbrain dopamine neurons.

    Fredric Manfredsson, PhD

    Fredric Manfredsson, PhD, is an associate professor in the Department of Neurobiology at Barrow Neurological Institute.

    Dr. Manfredsson’s expertise includes microbiology and virology, with a special interest in gene therapy for Parkinson disease and other neurodegenerative diseases. He is a member of the American Society for Gene & Cell Therapy, The American Society for Neural Therapy and Repair, and the Society for Neuroscience.

    Dr. Manfredsson earned his doctorate degree in neuroscience from the University of Florida in Gainesville, where he also completed a postdoctoral fellowship in neuroscience.

    Dr. Manfredsson’s research has multiple focuses. One aspect is to better understand the role of the protein alpha-synuclein in both healthy cells and those affected by Parkinson’s disease. His research also emphasizes understanding the symptomology of the disease, with a focus on the treatment of levodopa-induced dyskinesia and nonmotor symptoms experienced by nearly all patients with Parkinson’s disease.

    Teddy Youn, MD

    Bryan Lee, MD

    Bryan Lee, MD, is a neurosurgeon in the Department of Neurosurgery at Barrow Neurological Institute.

    Dr. Lee specializes in minimally invasive spine surgery and complex spinal deformity correction. He treats spinal deformities, spinal degenerative diseases, cranial and spinal trauma, and brain and spinal tumors. He is a member of the American Association of Neurological Surgeons, AOSpine North America, the Congress of Neurological Surgeons, and the North American Spine Society.

    Dr. Lee earned his medical degree from the Loma Linda University School of Medicine in California. He completed his residency in neurosurgery and a fellowship in spine surgery at Cleveland Clinic.

    Dr. Lee’s research interests include comparative analyses of clinical outcome data to optimize health-related quality of life in patients and clinical and biomechanical studies of the latest technology to treat complex spinal diseases.

    To request an appointment with Dr. Lee, please call (623) 562-5050.

    About Barrow Neurological Institute

    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.