Andrej Romanovsky, MD, PhD, is an integrative physiologist studying body temperature regulation and systemic inflammation. Originally from St. Petersburg, Russia, Dr. Romanovsky was granted his MD with Distinction by the Ivan Pavlov Medical University (St. Petersburg) in 1984. He completed his pathophysiology residency in 1986 at the Pavlov Institute of Experimental Medicine of the Russian Academy of Medical Sciences in St. Petersburg.
In 1989, he received a PhD in physiology from the Institute of Physiology of the National Academy of Sciences (Minsk, Belarus) and at the age of 29 became the youngest Senior Scientist in the history of that institute. Following postdoctoral training at the University of Tennessee Medical School in Memphis (1991–1994) and several months of work as a visiting scientist at the University of Pécs Medical School (Hungary, 1991) and University of Kanazawa Medical School (Japan, 1994), Dr. Romanovsky accepted the position of Associate Scientist and Director of the Thermoregulation Laboratory at the Legacy Health System in Portland, Oregon (1994–2000). In December of 1999, he joined St. Joseph’s Hospital and Medical Center in Phoenix as a Full Professor to direct the Systemic Inflammation Laboratory (FeverLab), a part of the hospital’s Trauma Program. He also holds an Adjunct Professor appointment at the Arizona State University (ASU) School of Life Sciences and serves as a faculty member of the joint Interdisciplinary Graduate Program in Neuroscience of Barrow Neurological Institute and ASU.
Dr. Romanovsky has published more than 100 articles in peer-reviewed scientific journals, including Pharmacological Reviews, Nature Neuroscience, PLoS Biology, Progress in Lipid Research, Blood, Clinical Infectious Diseases, and others. He is the founding Editor-in-Chief of the journal Temperature. He has served on study sections and reviewed grant applications for the National Institutes of Health, the National Science Foundation, the Medical Research Council (UK), the Canadian Institutes of Health Research, the Swedish Research Council, the Dutch Research Council, the National Research Foundation (South Africa), the National Council of Romania, the Polish National Science Center, the government of Hong Kong, and other agencies. Dr. Romanovsky’s research has been funded by the National Institutes of Health, the State of Arizona, and a number of pharmaceutical companies and foundations.
- Wanner SP, Almeida MC, Shimansky YP, Oliveira DL, Eales JR, Coimbra CC, Romanovsky AA. Cold-induced thermogenesis and inflammation-associated cold-seeking behavior are represented by different dorsomedial hypothalamic sites: a three-dimensional functional topography study in conscious rats. J Neurosci. 2017;37(29):6956-6971.
- de Oliveira C, Garami A, Lehto SG, Pakai E, Tekus V, Pohoczky K, Youngblood BD, Wang W, Kort ME, Kym PR, Pinter E, Gavva NR, Romanovsky AA. Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents. J Neurosci. 2014;34(13):4445-4452.
- Saper CB, Romanovsky AA, Scammell TE. Neural circuitry engaged by prostaglandins during the sickness syndrome. Nat Neurosci. 2012;15(8):1088-1095.
- Almeida MC, Hew-Butler T, Soriano RN, Rao S, Wang W, Wang J, Tamayo N, Oliveira DL, Nucci TB, Aryal P, Garami A, Bautista D, Gavva NR, Romanovsky AA. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. J Neurosci. 2012;32(6):2086-2099.
- Garami A, Pakai E, Oliveira DL, Steiner AA, Wanner SP, Almeida MC, Lesnikov VA, Gavva NR, Romanovsky AA. Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. J Neurosci. 2011;31(5):1721-1733.
- Garami A, Shimansky YP, Pakai E, Oliveira DL, Gavva NR, Romanovsky AA. Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia. J Neurosci. 2010;30(4):1435-1440.
- Romanovsky AA, Almeida MC, Garami A, Steiner AA, Norman MH, Morrison SF, Nakamura K, Burmeister JJ, Nucci TB. The transient receptor potential vanilloid-1 channel in thermoregulation: a thermosensor it is not. Pharmacol Rev. 2009;61(3):228-261.
- Steiner AA, Turek VF, Almeida MC, Burmeister JJ, Oliveira DL, Roberts JL, Bannon AW, Norman MH, Louis JC, Treanor JJ, Gavva NR, Romanovsky AA. Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci. 2007;27(28):7459-7468.
- Steiner AA, Ivanov AI, Serrats J, Hosokawa H, Phayre AN, Robbins JR, Roberts JL, Kobayashi S, Matsumura K, Sawchenko PE, Romanovsky AA. Cellular and molecular bases of the initiation of fever. PLoS Biol. 2006;4(9):e284.
- Steiner AA, Chakravarty S, Rudaya AY, Herkenham M, Romanovsky AA. Bacterial lipopolysaccharide fever is initiated via Toll-like receptor 4 on hematopoietic cells. Blood. 2006;107(10):4000-4002.