Andrej A. Romanovsky, MD, PhD, is an integrative physiologist and neuroscientist studying body temperature regulation and systemic inflammation.Originally from St. Petersburg, Russia, Dr. Romanovsky was granted his MD with Distinction by the Ivan Pavlov Medical University (St. Petersburg) in 1984. He completed his pathophysiology residency in 1986 at the Pavlov Institute of Experimental Medicine of the Russian Academy of Medical Sciences in St. Petersburg. In 1989, he received a PhD in physiology from the Institute of Physiology of the National Academy of Sciences (Minsk, Belarus). Following postdoctoral training in neuroscience at the University of Tennessee Medical School in Memphis (1991–1994), Dr. Romanovsky accepted the position of Associate Scientist and Director of the Thermoregulation Laboratory at the Legacy Health System in Portland, Oregon (1994–2000). Since 1999, he has been working as Professor, Trauma Research, at St. Joseph’s Hospital and Medical Center in Phoenix, Arizona, where he directs his basic research laboratory, FeverLab. He also holds an Adjunct Professor appointment at the Arizona State University School of Life Sciences and the Interdisciplinary Graduate Program in Neuroscience in Tempe, Arizona.
Dr. Romanovsky has published more than 120 articles in peer-reviewed scientific journals, including Blood, Clinical Infectious Diseases, Journal of Neuroscience, Nature Neuroscience, Pain, Pharmacological Reviews, PLoS Biology, and others. His research has been featured by Current Biology, Faculty of 1000, Nature Reviews Neuroscience, Scientific American, and other publications. His research has been funded by the National Institutes of Health, the State of Arizona, and a number of pharmaceutical companies and foundations. Dr. Romanovsky has served on study sections and reviewed grant applications for the National Institutes of Health (including the EUREKA program), the National Science Foundation, the Medical Research Council (UK), the Canadian Institutes of Health Research, the Swedish Research Council, the Dutch Research Council, the National Research Foundation (South Africa), the National Council of Romania, the Polish National Science Center, the government of Hong Kong, and other agencies in many countries. He has served on boards of several journals, including the American Journal of Physiology (Regulatory, Integrative and Comparative Physiology), PLoS One (Academic Editor), and Acta Physiologica Hungarica (International Board). He is the founding Editor-in-Chief of the journal Temperature and the volume editor of two volumes of the Handbook of Clinical Neurology. Dr. Romanovsky is a board member and Chief Scientific Officer (thermoregulation) of Catalina Pharma, Inc. Dr. Romanovsky also writes on science history, the scientist’s role in society, sustainability, and other topics. His letters and essays have been published by Cell Cycle, Lancet, Nature, Northwest Woodlands, and other publications.
- Wanner SP, Almeida MC, Shimansky YP, Oliveira DL, Eales JR, Coimbra CC, Romanovsky AA. Cold-induced thermogenesis and inflammation-associated cold-seeking behavior are represented by different dorsomedial hypothalamic sites: a three-dimensional functional topography study in conscious rats. J Neurosci. 2017;37(29):6956-6971.
- de Oliveira C, Garami A, Lehto SG, Pakai E, Tekus V, Pohoczky K, Youngblood BD, Wang W, Kort ME, Kym PR, Pinter E, Gavva NR, Romanovsky AA. Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents. J Neurosci. 2014;34(13):4445-4452.
- Saper CB, Romanovsky AA, Scammell TE. Neural circuitry engaged by prostaglandins during the sickness syndrome. Nat Neurosci. 2012;15(8):1088-1095.
- Almeida MC, Hew-Butler T, Soriano RN, Rao S, Wang W, Wang J, Tamayo N, Oliveira DL, Nucci TB, Aryal P, Garami A, Bautista D, Gavva NR, Romanovsky AA. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. J Neurosci. 2012;32(6):2086-2099.
- Garami A, Pakai E, Oliveira DL, Steiner AA, Wanner SP, Almeida MC, Lesnikov VA, Gavva NR, Romanovsky AA. Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. J Neurosci. 2011;31(5):1721-1733.
- Garami A, Shimansky YP, Pakai E, Oliveira DL, Gavva NR, Romanovsky AA. Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia. J Neurosci. 2010;30(4):1435-1440.
- Romanovsky AA, Almeida MC, Garami A, Steiner AA, Norman MH, Morrison SF, Nakamura K, Burmeister JJ, Nucci TB. The transient receptor potential vanilloid-1 channel in thermoregulation: a thermosensor it is not. Pharmacol Rev. 2009;61(3):228-261.
- Steiner AA, Turek VF, Almeida MC, Burmeister JJ, Oliveira DL, Roberts JL, Bannon AW, Norman MH, Louis JC, Treanor JJ, Gavva NR, Romanovsky AA. Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci. 2007;27(28):7459-7468.
- Steiner AA, Ivanov AI, Serrats J, Hosokawa H, Phayre AN, Robbins JR, Roberts JL, Kobayashi S, Matsumura K, Sawchenko PE, Romanovsky AA. Cellular and molecular bases of the initiation of fever. PLoS Biol. 2006;4(9):e284.
- Steiner AA, Chakravarty S, Rudaya AY, Herkenham M, Romanovsky AA. Bacterial lipopolysaccharide fever is initiated via Toll-like receptor 4 on hematopoietic cells. Blood. 2006;107(10):4000-4002.