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    James Frey, MD

    Stroke (480) 787-2284

    James Frey, MD, is the founder of the Stroke Program at Barrow Neurological Institute at Dignity Health St. Joseph’s Hospital and Medical Center in Phoenix. Dr. Frey is certified by the American Board of Medical Specialties (Vascular Neurology) and the American Board of Psychiatry and Neurology. He is a fellow of the American Academy of Neurology and the American Heart and Stroke Association.

    Dr. Frey specializes in stroke and cerebrovascular disease. He has authored more than 50 scientific publications, given more than 50 scientific presentations, and has been principal investigator in more than 40 research trials in stroke and Alzheimer’s disease.

    Dr. Frey graduated from Amherst College in Amherst, Massachusetts, and received his medical degree from Duke University School of Medicine in Durham, North Carolina, where he was a Mary Biddle Duke Tuition scholar and a member of Alpha Omega Alpha (AOA) Medical Honor Society. He obtained his neurology training at University of Chicago and Washington University in St. Louis.

    Teaching and mentoring residents and students are Dr. Frey’s passions. He has been honored multiple times as the Teacher of the Year in the Department of Neurology at Barrow. All of the stroke fellows trained by Dr. Frey have become stroke program directors or members of academic stroke programs.

    For more information or to request an appointment, please call (480) 787-2284.

    Fax: (602) 406-6261

    Education & Training
    • Residency, University of Chicago and Washington University, Neurology, 1976
    • Internship, University of Chicago, Medicine, 1972-1973
    • MD, Duke University School of Medicine, 1972
    • BA, Amherst College, 1968
    Professional Memberships
    • Clinical Professor of Neurology, University of Arizona School of Medicine
    • President, American Heart and Stroke Association, Phoenix Metro Board
    • Member, American Heart and Stroke Association, National Stroke Advisory Committee
    • Member, Executive Committee, American Academy of Neurology, Interventional Neurology Section
    • Examiner, American Board of Psychiatry and Neurology
    • Founder and Director, Barrow Neurological Institute Stroke Database
    • Founder and Director, St. Joseph’s Hospital Cerebrovascular Ultrasound Laboratory
    • Reviewer, Stroke, Neurology, Journal of Stroke and Cerebrovascular Disease, Cerebrovascular Disease, Canadian Journal of Neurological Sciences
    Selected Publications
    1. Chang J, Darbonne C, Drumm DA, Teleb MS, Frey JL. Need for Performance Protocols in TEE and TCD for Detection of Right to Left Shunts. J Neuroimaging. 2012 Aug 22.
    2. Chang J, Teleb M, Yang JP, Alderazi YJ, Chapple K, Frey JL, Restrepo L. A model to prevent fibrinolysis in patients with stroke mimics. J Stroke Cerebrovasc Dis. Nov 2012;21(8):839-843.
    3. Tsivgoulis G, Frey JL, Flaster M, Sharma VK, Lao AY, Hoover SL, Liu W, Stamboulis E, Alexandrov AW, Malkoff MD, Alexandrov AV. Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage. Stroke. Nov 2009;40(11):3631-3634.
    4. Romero JR, Frey JL, Schwamm LH, Demaerschalk BM, Chaliki HP, Parikh G, Burke RF, Babikian VL. Cerebral ischemic events associated with ‘bubble study’ for identification of right to left shunts. Stroke. Jul 2009;40(7):2343-2348.
    5. Pancioli AM, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J, Jr., Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman RJ. The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke. Dec 2008;39(12):3268-3276.
    6. Lao AY, Sharma VK, Tsivgoulis G, Frey JL, Malkoff MD, Navarro JC, Alexandrov AV. Detection of right-to-left shunts: comparison between the International Consensus and Spencer Logarithmic Scale criteria. J Neuroimaging. Oct 2008;18(4):402-406.
    7. Frey JL, Jahnke HK, Goslar PW. Study of the propensity for hemorrhage in Hispanic Americans with stroke. J Stroke Cerebrovasc Dis. Mar-Apr 2008;17(2):58-63.
    8. Lao AY, Sharma VK, Tsivgoulis G, Malkoff MD, Alexandrov AV, Frey JL. Effect of body positioning during transcranial Doppler detection of right-to-left shunts. Eur J Neurol. Sep 2007;14(9):1035-1039.
    9. Frey JL. Recombinant tissue plasminogen activator (rtPA) for stroke. The perspective at 8 years. Neurologist. Mar 2005;11(2):123-133.

    About Barrow

    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premiere destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.