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Chad Quarles, PhD
Chad Quarles, PhD, earned his undergraduate degree in biophysics at Centenary College of Louisiana in 1999 and his doctorate in biophysics at the Medical College of Wisconsin in 2004. He completed a postdoctoral fellowship in cancer imaging at Vanderbilt University Medical Center in 2006. Dr. Quarles stayed at Vanderbilt and attained the academic rank of associate professor in the Department of Radiology and the Vanderbilt University Institute of Imaging Science. He joined the faculty at Barrow in 2015.
Dr. Quarles’s research focuses on the development and application of multimodality imaging methods for improved disease characterization. He has a particular interest in leveraging all aspects of imaging science, including image acquisition and formation, contrast mechanisms, and image analysis, to discover novel imaging metrics and expand the clinical utility of bioimaging techniques.
When applied to brain cancer imaging, this philosophy has yielded more robust pulse sequences and postprocessing strategies for clinical perfusion imaging, a more comprehensive characterization of contrast agent induced susceptibility effects, and the new MR-based cytographic imaging technique.
Dr. Quarles’s research has been continuously funded through multiple grants from the National Institutes of Health and the Department of Defense. At the national level, he is involved with initiatives (e.g. the Quantitative Imaging Network, the Quantitative Imaging Biomarkers Alliance, and the National Brain Tumor Society) that aim to standardize brain cancer imaging acquisition and analysis methods for clinical trials.
- Postdoctoral Fellowship, Vanderbilt University Institute of Imaging Science
- PhD, Medical College of Wisconsin, Biophysics, 2004
- BS, Centenary College of Louisiana, Biophysics, 1999
- International Society of Magnetic Resonance in Medicine
- Society of Nuclear Medicine and Molecular Imaging
Analysis of postprocessing steps for residue function dependent dynamic susceptibility contrast (DSC)-MRI biomarkers and their clinical impact on glioma grading for both 1.5 and 3T.
Date: 02/2020
Authors: Laura C Bell, A. Stokes, C. Quarles
Systematic assessment of multi-echo dynamic susceptibility contrast MRI using a digital reference object.
Date: 01/2020
Authors: A. Stokes, Natenael B Semmineh, Ashley Nespodzany, Laura C Bell, C. Quarles
Evaluating Multisite Rcbv Consistency From Dsc-Mri Imaging Protocols And Postprocessing Software Across The Nci Quantitative Imaging Network Sites Using A Digital Reference Object (Dro)
Date: 03/2019
Authors: Laura C. Bell, Natenael Semmineh, Hongyu An, Cihat Eldeniz, Richard Wahl, Kathleen M. Schmainda, Melissa A. Prah, Bradley J. Erickson, Panagiotis Korfiatis, Chengyue Wu, Anna G. Sorace, Thomas E. Yankeelov, Neal Rutledge, Thomas L. Chenevert, Dariya Malyarenko, Yichu Liu, Andrew Brenner, Lel S. Hu, Yuxiang Zhou, Jerrold L. Boxerman, Yi Fen Yen, Jayashree Kalpathy-Cramer, Andrew L. Beers, Mark Muzi, Ananth J. Madhuranthakam, Marco Pinho, Brian Johnson, C. Chad Quarles, C. Quarles
Imaging Vascular And Hemodynamic Features Of The Brain Using Dynamic Susceptibility Contrast And Dynamic Contrast Enhanced Mri
Date: 02/2019
Authors: C. Chad Quarles, C. Quarles, Laura C. Bell, Ashley M. Stokes, A. Stokes
Analysis Of Postprocessing Steps For Residue Function Dependent Dynamic Susceptibility Contrast (Dsc)-Mri Biomarkers And Their Clinical Impact On Glioma Grading For Both 1.5 And 3T
Date: 01/2019
Authors: Laura C. Bell, Ashley M. Stokes, A. Stokes, C. Chad Quarles, C. Quarles
- English


Chad Quarles, PhD
Chad Quarles, PhD, earned his undergraduate degree in biophysics at Centenary College of Louisiana in 1999 and his doctorate in biophysics at the Medical College of Wisconsin in 2004. He completed a postdoctoral fellowship in cancer imaging at Vanderbilt University Medical Center in 2006. Dr. Quarles stayed at Vanderbilt and attained the academic rank of associate professor in the Department of Radiology and the Vanderbilt University Institute of Imaging Science. He joined the faculty at Barrow in 2015.
Dr. Quarles’s research focuses on the development and application of multimodality imaging methods for improved disease characterization. He has a particular interest in leveraging all aspects of imaging science, including image acquisition and formation, contrast mechanisms, and image analysis, to discover novel imaging metrics and expand the clinical utility of bioimaging techniques.
When applied to brain cancer imaging, this philosophy has yielded more robust pulse sequences and postprocessing strategies for clinical perfusion imaging, a more comprehensive characterization of contrast agent induced susceptibility effects, and the new MR-based cytographic imaging technique.
Dr. Quarles’s research has been continuously funded through multiple grants from the National Institutes of Health and the Department of Defense. At the national level, he is involved with initiatives (e.g. the Quantitative Imaging Network, the Quantitative Imaging Biomarkers Alliance, and the National Brain Tumor Society) that aim to standardize brain cancer imaging acquisition and analysis methods for clinical trials.

- Postdoctoral Fellowship, Vanderbilt University Institute of Imaging Science
- PhD, Medical College of Wisconsin, Biophysics, 2004
- BS, Centenary College of Louisiana, Biophysics, 1999
- International Society of Magnetic Resonance in Medicine
- Society of Nuclear Medicine and Molecular Imaging
Analysis of postprocessing steps for residue function dependent dynamic susceptibility contrast (DSC)-MRI biomarkers and their clinical impact on glioma grading for both 1.5 and 3T.
Date: 02/2020
Authors: Laura C Bell, A. Stokes, C. Quarles
Systematic assessment of multi-echo dynamic susceptibility contrast MRI using a digital reference object.
Date: 01/2020
Authors: A. Stokes, Natenael B Semmineh, Ashley Nespodzany, Laura C Bell, C. Quarles
Evaluating Multisite Rcbv Consistency From Dsc-Mri Imaging Protocols And Postprocessing Software Across The Nci Quantitative Imaging Network Sites Using A Digital Reference Object (Dro)
Date: 03/2019
Authors: Laura C. Bell, Natenael Semmineh, Hongyu An, Cihat Eldeniz, Richard Wahl, Kathleen M. Schmainda, Melissa A. Prah, Bradley J. Erickson, Panagiotis Korfiatis, Chengyue Wu, Anna G. Sorace, Thomas E. Yankeelov, Neal Rutledge, Thomas L. Chenevert, Dariya Malyarenko, Yichu Liu, Andrew Brenner, Lel S. Hu, Yuxiang Zhou, Jerrold L. Boxerman, Yi Fen Yen, Jayashree Kalpathy-Cramer, Andrew L. Beers, Mark Muzi, Ananth J. Madhuranthakam, Marco Pinho, Brian Johnson, C. Chad Quarles, C. Quarles
Imaging Vascular And Hemodynamic Features Of The Brain Using Dynamic Susceptibility Contrast And Dynamic Contrast Enhanced Mri
Date: 02/2019
Authors: C. Chad Quarles, C. Quarles, Laura C. Bell, Ashley M. Stokes, A. Stokes
Analysis Of Postprocessing Steps For Residue Function Dependent Dynamic Susceptibility Contrast (Dsc)-Mri Biomarkers And Their Clinical Impact On Glioma Grading For Both 1.5 And 3T
Date: 01/2019
Authors: Laura C. Bell, Ashley M. Stokes, A. Stokes, C. Chad Quarles, C. Quarles
- English