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Research project: Mechanisms of synaptopathy in C9orf72 ALS/FTD using hiPSC-neurons and novel mouse models of C9orf72. Techniques applied to this project include confocal microscopy, live longitudinal survival studies of hiPSC-neurons, and live measurements of neuronal Ca homeostasis.
Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als
Date: 06/2019
Authors: Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G. O'Conner, Jordan M. Barrows, Alexander Starr, Tina Kovalik, Benjamin E. Rabichow, Erik M. Lehmkuhl, Dakotah D. Shreiner, Archi Joardar, Jean Charles Liévens, Robert Bowser, Rita Sattler, Daniela C. Zarnescu
Adar2 Mislocalization And Widespread Rna Editing Aberrations In C9Orf72-Mediated Als/Ftd
Date: 01/2019
Authors: Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis W. Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, Rita Sattler
Reactivation Of Nonsense-Mediated Mrna Decay Protects Against C9Orf72 Dipeptide-Repeat Neurotoxicity
Date: 01/2019
Authors: Wangchao Xu, Puhua Bao, Xin Jiang, Haifang Wang, Meiling Qin, Ruiqi Wang, Tao Wang, Yi Yang, Ileana Lorenzini, Lujian Liao, Rita Sattler, Jin Xu
Artificial Intelligence In Neurodegenerative Disease Research: Use Of Ibm Watson To Identify Additional Rna-Binding Proteins Altered In Amyotrophic Lateral Sclerosis
Date: 02/2018
Authors: Nadine Bakkar, Tina Kovalik, Ileana Lorenzini, Scott Spangler, Alix Lacoste, Kyle Sponaugle, Philip Ferrante, Elenee Argentinis, Rita Sattler, Robert Bowser
Tdp-43 Pathology Disrupts Nuclear Pore Complexes And Nucleocytoplasmic Transport In Als/Ftd
Date: 02/2018
Authors: Ching Chieh Chou, Yi Zhang, Mfon E. Umoh, Spencer W. Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G. Donlin-Asp, Yu Han Chen, Duc M. Duong, Nicholas T. Seyfried, Maureen A. Powers, Thomas Kukar, Chadwick M. Hales, Marla Gearing, Nigel J. Cairns, Kevin B. Boylan, Dennis W. Dickson, Rosa Rademakers, Yong Jie Zhang, Leonard Petrucelli, Rita Sattler, Daniela C. Zarnescu, Jonathan D. Glass, Wilfried Rossoll
- English
Research project: Mechanisms of synaptopathy in C9orf72 ALS/FTD using hiPSC-neurons and novel mouse models of C9orf72. Techniques applied to this project include confocal microscopy, live longitudinal survival studies of hiPSC-neurons, and live measurements of neuronal Ca homeostasis.
Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als
Date: 06/2019
Authors: Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G. O'Conner, Jordan M. Barrows, Alexander Starr, Tina Kovalik, Benjamin E. Rabichow, Erik M. Lehmkuhl, Dakotah D. Shreiner, Archi Joardar, Jean Charles Liévens, Robert Bowser, Rita Sattler, Daniela C. Zarnescu
Adar2 Mislocalization And Widespread Rna Editing Aberrations In C9Orf72-Mediated Als/Ftd
Date: 01/2019
Authors: Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis W. Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, Rita Sattler
Reactivation Of Nonsense-Mediated Mrna Decay Protects Against C9Orf72 Dipeptide-Repeat Neurotoxicity
Date: 01/2019
Authors: Wangchao Xu, Puhua Bao, Xin Jiang, Haifang Wang, Meiling Qin, Ruiqi Wang, Tao Wang, Yi Yang, Ileana Lorenzini, Lujian Liao, Rita Sattler, Jin Xu
Artificial Intelligence In Neurodegenerative Disease Research: Use Of Ibm Watson To Identify Additional Rna-Binding Proteins Altered In Amyotrophic Lateral Sclerosis
Date: 02/2018
Authors: Nadine Bakkar, Tina Kovalik, Ileana Lorenzini, Scott Spangler, Alix Lacoste, Kyle Sponaugle, Philip Ferrante, Elenee Argentinis, Rita Sattler, Robert Bowser
Tdp-43 Pathology Disrupts Nuclear Pore Complexes And Nucleocytoplasmic Transport In Als/Ftd
Date: 02/2018
Authors: Ching Chieh Chou, Yi Zhang, Mfon E. Umoh, Spencer W. Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G. Donlin-Asp, Yu Han Chen, Duc M. Duong, Nicholas T. Seyfried, Maureen A. Powers, Thomas Kukar, Chadwick M. Hales, Marla Gearing, Nigel J. Cairns, Kevin B. Boylan, Dennis W. Dickson, Rosa Rademakers, Yong Jie Zhang, Leonard Petrucelli, Rita Sattler, Daniela C. Zarnescu, Jonathan D. Glass, Wilfried Rossoll
- English