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    Molecular and Cellular Neuroscience

    Bowser Laboratory

    Our laboratory is at the forefront of using human patient samples to discover biochemical alterations that occur early in the disease process that reflect the underlying pathology of the disease and of using cell culture-based systems to further explore the…

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    Chang Laboratory

    The Chang Laboratory focuses on the structural basis of channel function in the cys-loop receptor family of ligand-gated ion channels. Dysfunction of these receptor/channels is implicated in the origin of a variety neurological and psychiatric disorders, including epilepsy, anxiety, schizophrenia,…

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    Gao Laboratory

    Mesocorticolimbic dopaminergic signaling, which originates in the dopamine (DA) neurons of the ventral tegmental area (VTA) and projects to the nucleus accumbens (NAc) and prefrontal cortex (PFC), governs the control of complex behaviors. Deregulation of…

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    Lukas-Whiteaker Laboratory

    The Laboratory of Neurochemistry, now jointly led by Drs. Paul Whiteaker and Ronald J. Lukas, focuses on nicotinic acetylcholine receptors, which are critical to chemical signaling and electrical wiring in the brain and body.

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    Mehta Laboratory

    The goal of the Mehta Laboratory is to elucidate the regulatory network of genes critical for glioma formation and their resistance to therapy. This will greatly augment our ability to identify a druggable factor that could be targeted for glioma…

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    Mufson Laboratory

    Research projects in the Mufson Laboratory focus on the pathobiology of the normal and diseased human brain, including the neurobiology of mild cognitive impairment, which is a precursor to Alzheimer’s disease (AD), Down syndrome, and…

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    Romanovsky Laboratory

    The Systemic Inflammation Laboratory (Fever Lab), headed by Andrej Romanovsky, MD, PhD., is a basic research unit of the Trauma Research Program of St. Joseph’s Hospital, a Level-1 Trauma Center.

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    Sanai Laboratory

    Our laboratory’s efforts are aimed at characterizing human GPCs and their germinal niche, and at developing a new set of human GPC-specific transcriptional and metabolic markers that enable real-time tracking of GPCs and glioma stem cells in live human brain.

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    Sattler Laboratory

    Lab Description Our laboratory studies the cellular and molecular mechanisms of neurodegeneration in central nervous system (CNS) disorders such as: amyotrophic lateral sclerosis (ALS) frontotemporal dementia (FTD) We are particularly interested in elucidating the role…

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    Scheck Laboratory

    The Scheck Laboratory’s work consists mainly of translational research to develop novel adjuvant therapies for the treatment of brain tumors. We also use various molecular and molecular genetic techniques to investigate why current therapies sometimes fail.

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    Shi Laboratory

    The Barrow Neuroimmunology Laboratory is a collaborative effort that encompasses the Neuroimmunology Regular Clinical Service Team, the Clinical Research Team, and the North American Research Committee on Multiple Sclerosis (NARCOMS) Project.

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    Sirianni Laboratory

    The primary goal of the Sirianni Laboratory is to engineer multifunctional nanocarriers for targeted treatment and imaging of brain tumors, with a focus on developing technologies that have the potential for clinical translation.

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    Wu Laboratory

    Dr. Wu and his team are studying the function and pharmacology of heterologously expressed nAChRs in cloned cells and native nAChRs in neurons isolated from brain tissue. Using electrophysiological techniques we are working to elucidate the mechanisms of nicotine reward,…

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    About Barrow

    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premiere destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.