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  • Molecular and Cellular Neuroscience

    Bowser Laboratory

    Our laboratory is at the forefront of using human patient samples to discover biochemical alterations that occur early in the disease process that reflect the underlying pathology of the disease and of using cell culture-based systems to further explore the…

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    Gao Laboratory

    Mesocorticolimbic dopaminergic signaling, which originates in the dopamine (DA) neurons of the ventral tegmental area (VTA) and projects to the nucleus accumbens (NAc) and prefrontal cortex (PFC), governs the control of complex behaviors. Deregulation of…

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    Lukas-Whiteaker Laboratory

    The Laboratory of Neurochemistry, now jointly led by Drs. Paul Whiteaker and Ronald J. Lukas, focuses on nicotinic acetylcholine receptors, which are critical to chemical signaling and electrical wiring in the brain and body.

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    Mehta Laboratory

    Laboratory Focus The Mehta Laboratory studies the biology of malignant gliomas, including glioblastoma, anaplastic astrocytoma, and oligodendrogliomas. Specifically, we are interested in identifying the signaling pathways that are critical for the survival of therapy-resistant, stem-like…

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    Mufson Laboratory

    Research projects in the Mufson Laboratory focus on the pathobiology of the normal and diseased human brain, including the neurobiology of mild cognitive impairment, which is a precursor to Alzheimer’s disease (AD), Down syndrome, and…

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    Sanai Laboratory

    Our laboratory’s efforts are aimed at characterizing human GPCs and their germinal niche, and at developing a new set of human GPC-specific transcriptional and metabolic markers that enable real-time tracking of GPCs and glioma stem cells in live human brain.

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    Sattler Laboratory

    Lab Description Our laboratory studies the cellular and molecular mechanisms of neurodegeneration in central nervous system (CNS) disorders such as: amyotrophic lateral sclerosis (ALS) frontotemporal dementia (FTD) We are particularly interested in elucidating the role…

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    Wu Laboratory

    Dr. Wu and his team are studying the function and pharmacology of heterologously expressed nAChRs in cloned cells and native nAChRs in neurons isolated from brain tissue. Using electrophysiological techniques we are working to elucidate the mechanisms of nicotine reward,…

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    About Barrow Neurological Institute

    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.