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    Sattler Laboratory News


    Sattler Laboratory members and other participants at the Walk to Defeat ALS.

    May 2018

    The lab has been incredibly busy over the last six months. Here are a few highlights of what has been going on:

    Career developments

    • Both Layla and Alex are moving on to graduate school this fall. Layla will join the Neuroscience Graduate Program at Thomas Jefferson University, and Alex accepted an offer from the graduate program in the Department of Pharmacology at University of Pennsylvania. We wish them both the best of luck and will certainly miss them!
    • Our high school students Devika and Nancy are heading to college! Devika will be joining UCLA, while Nancy will head to ASU Barrett Honors College with a Flinn Foundation Scholarship. Congratulations to both of them!!

    New lab members

    • In October last year, Divya Bhatia joined the Sattler Lab as an undergraduate student from ASU and has since been an incredibly hard-working member of the lab.
    • In November last year, Kevin Ma joined the Sattler Lab as a research technician. Welcome on board, Kevin!
    • Ashley Nelson, a MD/PhD student from UofA College of Medicine Phoenix, did a research lab rotation in the Sattler Lab from Jan-April, studying the role of TDP43 in ALS/FTD.

    Science updates

    • In September last year, we hosted our Second Annual Arizona ALS Symposium, this time at Biosphere 2. The symposium was attended by close to 60 participants from all over the state of Arizona and was a great success.
    • In December, Dr. Sattler in collaboration with Dr. Salvatore Oddo (ASU) hosted the first Neuro Division meeting for the Arizona Wellbeing Commons.
    • The Sattler Lab co-authored two papers in collaboration with Dr. Robert Bowser’s laboratory (BNI) and Dr. Wilfried Rossoll’s laboratory (Mayo Clinic Jacksonville, FL):

    See also the following link:

    • Two invited review articles were published, one in the Special Edition of Brain Research and one in a Special Issue of Frontiers in Neuroscience, first-authored by Alex and Layla, respectively. Congratulations!!

    • The lab has a strong presence with numerous poster presentations at SFN 2017 in Washington, DC.
    • Sattler lectured again at the Wellcome Trust Neurodegeneration Course in Hinxton/Cambridge, UK. This year, Stephen was one of the students attending the course!
    • Some of the members from the lab attended the annual Robert Packard Center Research symposium in Baltimore, MD! Always a great meeting with lots of new and exciting science!

    Funding updates

    • Stephen was awarded a BNI Neurobiology science award
    • The Sattler Lab, in collaboration with Dr. Daniela Zarnescu’s lab (UofA Tucson), was awarded a DOD research grant
    • The Sattler Lab was awarded a grant from the Robert Packard Center for ALS Research

    Other noteworthy news

    • In October last year, the lab participated for the third year in the AZ ALSA walk with team “Fulton ALS Center” and raised a record high number in funds towards the Arizona ALSA chapter! Congratulations everybody, and thanks to those who supported us.
    • Doug, our ALS patient volunteer, was featured on the Barrow Newsletter and Barrow Facebook page. We are all so proud of Doug and all he does to advocate for ALS research!!
    • Stephen and Dr. Sattler are participating in the ‘Climb to defeat ALS’, which raises funds for the ALS Association. The two will climb Mt. Elbert in Colorado, the highest 14er of the Rocky Mountains in North America. Please support team “Barrow Brainiacs” for this incredible adventure by donating money towards their fundraising efforts here.

    September 2017

    • A collaborative study under the leadership of Dr. Daniela Zarnescu’s laboratory at University of Arizona was accepted for publication at Cell Press! Congratulations to everybody!
    • The Sattler Lab welcomes yet another research volunteer to the lab: Doug Clough – ALS patient, advocate, and ambassador!!! We are extremely excited to give Doug an opportunity to, as he says, ‘own his disease’ by having him work alongside the researchers in the lab. We keep questioning who is more excited about this opportunity, him or us?! Welcome, Doug!

    August 2017

    • Abigail and Nancy participated at the Barrow summer intern research symposium. Abigail gave a brilliant slide presentation, and Nancy effortlessly mastered her poster presentation. We are very proud of these two incredibly talented young scientists! Congratulations!
    • Welcome to our new high school student intern, Shiv Shah. Shiv is a junior at Mountain Ridge High School.

    July 2017

    • Andrew left the Sattler Lab and Arizona to start his PhD program in Neuroscience at Thomas Jefferson University! Congratulations again and good luck to his future studies!
    • Stephen presented his thesis project at the Barrow Tuesday seminar series. This was his first big audience presentation, and he excelled easily!
    • Some of the Sattler Lab members attended the inaugural Gordon Conference on “ALS and related motor neuron diseases,” co-chaired by Dr. Sattler. Great science discussions in beautiful Vermont.

    June 2017

    • The lab welcomes our summer student Abigail Byford from the University of Leeds, UK, and Michael Goldstein, an undergraduate student from ASU.
    • With 19:26 minutes left, the lab escaped successfully from the Pearled Pachyderm at the Phoenix Puzzle Room. One of the fastest groups to make it out of the room! Great team effort!!
    • Ileana was awarded a postdoctoral fellowship award by the Barrow Neurological Foundation to study mechanisms of synaptic dysfunction in ALS and related disorders. Congratulations, Ileana!
    • Nancy made headlines in the news when she was included in an article about women in STEM.

    May 2017

    • Stephen won the ASU Graduate and Professional Student Association (GPSA) Individual Travel Grant to present a poster at this year’s Gordon Conference on ALS. Congratulations, Stephen!
    • In collaboration with the Mufson Laboratory, the Sattler Laboratory was awarded a research grant from the Barrow Neurological Foundation/Arizona Alzheimer’s Research Consortium (AARC) to study mechanisms of Down syndrome neurodegeneration in patient-derived iNeurons
    • The lab had its second annual Salt River Tubing adventure – without any sunburns this year!
    • Dr. Sattler participated in her first Barrow Neurological Institute Grand Canyon Rim-to-Rim hike! She made it through without major problems and is planning on a Rim-to-Rim-to-Rim for next year!

    April 2017

    • Devika presented a poster and won third place at the 2017 Arizona Science and Engineering Fair (AzSEF). Congratulations, Devika!
    • The lab did a weekend camping trip to Prescott, Arizona. Lots of relaxing, hiking, cooking, and eating!
    • The lab was awarded a pilot grant from the Arizona Alzheimer’s Disease Core Center (ADCC) to study patient-derived iPSC microglial cells in C9orf72 ALS/FTD

    March 2017

    • On March 2, Camelia gave birth to a healthy baby boy, Stefan. Everybody is excited about our first lab baby!
    • Andrew was accepted into the neuroscience graduate program at Thomas Jefferson University in Philadelphia. Congratulations, Andrew!
    • Layla Ghaffari joined the laboratory as a research technician.
    • Ileana was invited to give a presentation at the Synapses and Circuits: Formation, Function and Dysfunction Keystone Symposium in Santa Fe, New Mexico.

    February 2017

    • Devika won first place at the BASIS High School Science Fair and is moving on to compete at the 2017 Arizona Science and Engineering Fair (AzSEF) to be held in April in Phoenix. Congratulations, Devika!

    January 2017

    • Stephen received a graduate student spring fellowship from Arizona State University.
    • Sarah was awarded a Bidstrup Undergraduate Fellowship to support her honor’s thesis research project.
    • The laboratory was awarded a research grant by the Robert Packard Center for ALS Research.

    December 2016

    • Dr. Rita Sattler and Dr. Stella Dracheva of the Icahn School of Medicine at Mount Sinai were awarded a grant from the Department of Veterans Affairs to study the role of ADAR2-associated RNA editing in ALS.
    • Congratulations to Camelia Burciu! She is expecting a baby boy, and we are very happy for her!

    November 2016

    • Members of the Sattler Laboratory presented at two scientific conferences. Dr. Ileana Lorenzini presented work regarding GluA2 misediting in ALS at the 4th RNA Metabolism in Neurological Disease Satellite Meeting of the 11th Brain Research Conference and at the 2016 Society for Neuroscience (SfN) Annual Meeting, both in San Diego, California. Alex Starr also presented work investigating the role of a copper transporter mutation in ALS at the 2016 SfN Meeting.

    October 2016

    • The Sattler Laboratory, along with colleagues from Barrow Neurological Institute and other institutions, participated in the ALS Association’s Walk to Defeat ALS in Scottsdale, Arizona. The annual walk supports the Arizona chapter of the ALS Association in its mission to fund ALS research and provide care for patients. Researchers, family, and friends filled Scottsdale Stadium and raised over $470,000!

    September 2016

    • Camelia Burciu joined the laboratory as a research technician.
    • Nancy Twishime gave a poster presentation summarizing her summer research at the Arizona Biosciences event.
    • The Downtown Devil reported on our collaboration with Dr. Kruer’s Laboratory.
    • The lab gathered at Dr. Sattler’s house for an end-of-the-summer pool party.
    • Dr. Rita Sattler and Dr. Robert Bowser organized and chaired the Inaugural Arizona ALS Symposium. It was attended by more than 35 scientists and clinicians representing universities, nonprofits, hospitals, and the biomedical industry across Arizona. Over the course of three days, participants shared their work, formed new collaborations, and brainstormed future projects to expand our understanding and treatment of ALS.

    August 2016

    • Andrew Nelson joined the laboratory as a research technician.
    • Devika Shenoy, from BASIS High School in Scottsdale, joined the laboratory as an intern.
    • The staff of the laboratory had a great time and grew as a team while tubing down the Salt River.
    • Nancy gave an oral presentation of her summer research at the annual Barrow summer research student day.
    • Sarah started her senior thesis project in our laboratory.

    July 2016

    June 2016

    • Stephen Moore joined the lab as a graduate student in neuroscience.
    • Sara Swinford, an undergraduate student at ASU, began a summer internship with the laboratory.
    • Nancy Twishime, a student at Bioscience High School in Phoenix, joined the laboratory as a summer intern.
    • The laboratory was awarded a grant with the Kruer Laboratory at Phoenix Children’s Hospital from the Research Development and Partnership Initiative (RDPI) to study genetic forms of cerebral palsy.

    April 2016

    • The first hiPSC neurons are differentiating in the new desert climate.
    • All new microscopes are up and running.

    March 2016

    • Stephen joined the laboratory as a Neuroscience graduate student on June 1.
    • Sarah joined the laboratory as an undergraduate research summer intern on June 1.

    February 2016

    • Ileana received an invitation to submit a postdoctoral fellowship application to the ALS association (ALSA).
    • Ileana received a travel award for the American Society for Neurochemistry (ASN) Meeting in Denver, Colorado.

    January 2016

    • Isaiah Tesfay joined the laboratory as an undergraduate research assistant.
    • The laboratory received renewed funding from the Robert Packard Center for ALS Research.
    • Alex Starr joined the laboratory as a new research technician.

    November 2015

    • Ileana arrived in Phoenix and rejoined the Sattler Laboratory.

    October 2015

    • Dr. Sattler and Jenny started setting up the Sattler Laboratory at Barrow.

    About Barrow

    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.