Collaborators: Beloozerova Lab
Boris Prilutsky, PhD
School of Biological Sciences
Georgia Institute of Technology, Atlanta, GA
Research in the laboratory of Dr. Prilutsky focuses on the mechanisms of movement generation and control. This includes control of force by the arm during learning new movements, modeling of the spinal cord neural circuitry that controls locomotion, and studying the role of the motor cortex in different locomotor behaviors.
We collaborate with the laboratory of Dr. Prilutsky in the analysis of biomechanics of complex locomotion behaviors and involvement of motor cortex in the control of them. We conduct experiments together in Phoenix recording whole-body kinematics and dynamics of subjects while they walk along a cluttered pathway, along series of elevated platforms, along a narrow strip, or on other complex surfaces. We also record the activity of muscles and the motor region of the cerebral cortex the same time. The goal is to describe, analyze, and eventually understand biomechanics of complex locomotion behaviors, and their neural correlates.
Tatiana Deliagina, PhD, and Grigory Orlovsky, PhD
Department of Neuroscience
Karolinska Institute in Stockholm, Sweden
The general goal of research in the laboratory of Dr. Deliagina is to understand the organization and operation of the neuronal networks responsible for maintenance of the basic body posture.
We collaborate with the laboratory of Dr. Deliagina in studies aimed at characterizing the commands that are transmitted from the brain motor centers to the spinal cord during different postural tasks. In our joint experiments, we test subjects while they balance on a platform that periodically tilts to the right and then to the left. The subjects assume different postures (such as leaning to the right or to the left) or perform stepping movements while still keeping balance on the platform. We record kinematics and dynamic parameters of limbs and body movements, the activity of limb muscles, and the neuonal activity of the motor cortex, motor thalamus, and midbrain. We then compare body mechanics, the activity of muscles, and the activity of brain areas during balancing with different postural configurations and reveal the parameters, which are associated specifically with each of the configurations. This allows us to understand the contribution of supraspinal mechanisms to the control of posture.
Oleg Favorov, PhD
Dr. Favorov’s research interests revolve around neural bases of perception, somatosensory cortical physiology, and pattern recognition. Dr. Favorov studies:
- Neural bases of perception, with special emphasis on the relationship between patterns of neuroelectrical activity in the somatosensory cerebral cortex and tactile perception
- Cortical information processing, with an emphasis on those computational algorithms that enable the cerebral cortex to recognize high-order regularities in observed phenomena and to take advantage of them in perceptual and decision-making tasks
- Physiological mechanisms responsible for generation of neuroelectrical activity in the cerebral cortex
- Computational algorithms for multivariate data analysis, machine learning, pattern recognition, and knowledge acquisition
We collaborate with Dr. Favorov on studies of neuronal behavior in the primary somatosensory cortex (SI) of cats during locomotion.