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    Gregory W. Fulton ALS Center

    ALS and Neuromuscular Disease Experts in Phoenix, Arizona

    Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

    Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a neurological disorder in which the body’s immune system attacks and damages the myelin sheath of the peripheral nerves.

    When this protective coating is damaged, nerve signals may be interrupted. This can lead to weakness and impaired sensory function in the arms and legs.

    Additional Information

    How common is chronic inflammatory demyelinating polyradiculoneuropathy?

    Chronic inflammatory demyelinating polyradiculoneuropathy is a rare disorder. There are about one to two new cases for every 100,000 people each year. However, because CIDP usually progresses slowly, a person may have it for years before a diagnosis is made.

    Who gets chronic inflammatory demyelinating polyradiculoneuropathy?

    Chronic inflammatory demyelinating polyradiculoneuropathy can occur at any age but is more common in young adults. It is also more common in men than in women.

    How is chronic inflammatory demyelinating polyradiculoneuropathy diagnosed?

    In addition to a physical exam, your doctor may use the following tests to diagnose chronic inflammatory demyelinating polyradiculoneuropathy:

    • electromyography
    • nerve conduction studies
    • blood tests
    • urine tests
    • lumbar puncture (spinal tap)
    • nerve biopsy
    Symptoms of Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

    Symptoms of chronic inflammatory demyelinating polyradiculoneuropathy usually progress slowly and may include:

    • tingling or numbness, beginning in your toes and fingers
    • weakness in your arms and legs
    • loss of reflexes
    • fatigue
    • pain
    • difficulty walking

    The presence of these symptoms does not necessarily mean you have CIDP, as they are shared with other conditions. Contact a medical professional if you are having symptoms.

    Treatments for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

    Treatment options for chronic inflammatory demyelinating polyradiculoneuropathy include:

    • corticosteroids, such as prednisone
    • plasmapheresis (plasma exchange)
    • intravenous immunoglobulin (IVIg) therapy
    • physical and occupational therapies

    Your prognosis may be better if the disease identified and treated early. People with CIDP will experience flare ups of their disease interspersed with periods of remission, but the duration and frequency of these relapses and remissions varies from person to person.

    • Date of last review: September 18, 2015