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  • Craniopharyngioma


    A craniopharyngioma is a rare type of brain tumor that forms near the pituitary gland, a small organ that secretes hormones that regulate many bodily functions. Most craniopharyngiomas are benign (noncancerous), but they exhibit locally aggressive behavior and will invade surrounding structures if left untreated. As the tumor grows, it can affect the function of the pituitary gland and other nearby structures.

    Additional Information

    How common are craniopharyngiomas?

    Craniopharyngiomas represent two to five percent of all primary brain tumors and five to 10 percent of all childhood brain tumors.

    Who gets craniopharyngiomas?

    Craniopharyngiomas can occur at any age and even before birth. However, they are most common in children between the ages of 5 and 14 and adults over 45. Both genders are equally affected. Craniopharyngiomas are more common in African-Americans than in other races.

    How are craniopharyngiomas diagnosed?

    Your doctor may use the following to diagnose a craniopharyngioma:

    • Neurological exam
    • Imaging tests, such as a CT scan or an MRI scan
    • Blood tests to measure hormone levels

    Symptoms of Craniopharyngioma

    Craniopharyngiomas are usually detected when they start to produce symptoms by pressing on the brain, pituitary gland, blood vessels, optic nerves, or optic chiasm (where the two optic nerves leading to the eyes intersect just before entering the brain). Symptoms vary greatly depending on how and where the tumor grows.

    The most common symptoms include:

    • Headache
    • Endocrine dysfunction
    • Vision problems

    If the tumor compresses the pituitary gland or pituitary stalk, it can cause the following:

    • Stunted growth
    • Delayed puberty
    • Loss of normal menstrual function
    • Loss of sexual desire
    • Increased sensitivity to cold
    • Fatigue
    • Constipation
    • Dry skin
    • Nausea
    • Low blood pressure
    • Depression
    • Diabetes insipidus
    • Excessive thirst
    • Excessive urination
    • Increased prolactin levels, which can cause milky discharge from breasts

    If the tumor compresses the optic nerve or chiasm, it can cause the following:

    • Blurred vision
    • Decreased visual field
    • Blindness

    If the tumor compresses the hypothalamus, it can cause the following:

    • Obesity
    • Increased drowsiness
    • Body temperature regulation abnormalities
    • Diabetes insipidus
    • Personality changes
    • Headache
    • Confusion
    • Vomiting

    Contact a medical professional if you are experiencing any symptoms.

    Treatments for Craniopharyngioma

    Surgery may be recommended to remove as much of the tumor as possible and to relieve pressure on the brain. The tumor may be removed through an opening in the skull (craniotomy) or through the nose using a small incision and specialized instruments (transsphenoidal surgery).

    If the entire tumor cannot be removed with surgery, radiation therapy may be suggested to stop further growth and kill the existing tumor cells. At Barrow Neurological Institute at Dignity Health St. Joseph’s Hospital and Medical Center, we offer noninvasive Gamma Knife and Cyberknife radiosurgery procedure that focus many small beams of radiation on the craniopharyngioma. We also offer transsphenoidal surgery and craniotomy to remove craniopharyngiomas.

    About Barrow Neurological Institute
    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.