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  • Neurodegenerative Disorders

    Neurodegenerative disorders are conditions that affect the nerve cells (neurons) in the brain and spinal cord, such as Alzheimer’s disease, Lou Gehrig’s disease, and Parkinson’s disease.

    Neurodegenerative disorders are incurable, often debilitating conditions that result in the progressive deterioration and death of neurons. This causes problems with movement, called ataxias, or mental functioning, called dementias.

    Additional Information

    How common are neurodegenerative disorders?

    The rate of neurodegenerative disorders varies with each type of disease. One in 10 people age 65 and older has Alzheimer’s disease, the most common neurodegenerative disorder.

    Who gets neurodegenerative disorders?

    There is no single cause of neurodegenerative disorders, making it difficult to say who is at risk. Many of these diseases are genetic. In other instances, they are caused by a medical condition such as alcoholism, brain injury, tumor, or stroke. Other causes may include toxins, chemicals, prion disease, or viruses. Sometimes the cause is not known.

    How are neurodegenerative disorders diagnosed?

    Precise determination of a neurodegenerative disorder can be elusive because it is often difficult to accurately differentiate one neurologic disease from another, particularly since many conditions may coexist.

    Symptoms of Neurodegenerative Disorders

    Some of the more common symptoms of neurodegenerative disorders may include:

    • A loss of inhibition
    • Anxiety
    • Agitation
    • Apathy
    • Difficulty with movement
    • Forgetfulness
    • Memory loss
    • Mood changes
    • Tremors or shaking

    Neurodegenerative disorders cause permanent damage to the nervous system. Symptoms tend to get worse as the disease progresses, and new symptoms are also likely to develop over time.

    Treatments for Neurodegenerative Disorders

    There is no cure for neurodegenerative disorders. Treatment may help improve symptoms, relieve pain, increase mobility, and maintain quality of life. Treatment often involves the use of medications to control symptoms.

    For people diagnosed with a subset of neurodegenerative disorders called movement disorders, a surgical procedure called deep brain stimulation, or DBS, may provide considerable symptom relief.

    Information and Resources

    Medline Plus


    Request an Appointment with a Neurodegenerative Disease Specialist

    Call (602) 406-6262

    • Date of last review: January 2, 2020

    About Barrow Neurological Institute
    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.