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Fredric Manfredsson, PhD
Gene Therapy, Parkinson's
Fredric Manfredsson, PhD, is an associate professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Manfredsson’s expertise includes microbiology and virology, with a special interest in gene therapy for Parkinson’s disease and other neurodegenerative diseases. He is a member of the American Society for Gene & Cell Therapy, The American Society for Neural Therapy and Repair, and the Society for Neuroscience.
Dr. Manfredsson earned his doctorate degree in neuroscience from the University of Florida in Gainesville, where he also completed a postdoctoral fellowship in neuroscience.
Dr. Manfredsson’s research has multiple focuses. One aspect is to better understand the role of the protein alpha-synuclein in both healthy cells and those affected by Parkinson’s disease. His research also emphasizes understanding the symptomology of the disease, with a focus on the treatment of levodopa-induced dyskinesia and nonmotor symptoms experienced by nearly all patients with Parkinson’s disease.
- Postdoctoral Fellowship, University of Florida, Department of Neuroscience, 2006-2010
- PhD, University of Florida, Graduate Program in Biomedical Sciences, Neuroscience, 2006
- BS, Arizona State University, Microbiology, 1999
- President, American Society for Neural Therapy and Repair, 2018-2020
- Fellow, American Society for Neural Therapy and Repair, 2015-Present
- Cover Image, Molecular Therapy, June 2009, March 2015
- Julius Axelrod Travel Award, Society for Neuroscience, 2011
- Alumni Fellowship, University of Florida, 2001-2005
- American Society for Gene & Cell Therapy
- The American Society for Neural Therapy and Repair
- Society for Neuroscience
2021 Workshop: Neurodegenerative Diseases in the Gut-Brain Axis - Parkinson's Disease
Date: 02/2022
Authors: Gary M. Mawe, Kirsteen N. Browning, Fredric P. Manfredsson, Michael Camilleri, Frank A. Hamilton, Jonathan A. Hollander, Beth-Anne Sieber, Patricia Greenwel, Terez Shea-Donohue, John W. Wiley
Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease
Date: 12/2021
Authors: Juozas Gordevicius, Peipei Li, Lee L. Marshall, Bryan A. Killinger, Sean Lang, Elizabeth Ensink, Nathan C. Kuhn, Wei Cui, Nazia Maroof, Roberta Lauria, Christina Rueb, Juliane Siebourg-Polster, Pierre Maliver, Jared Lamp, Irving Vega, Fredric P. Manfredsson, Markus Britschgi, Viviane Labrie
Orexin (hypocretin) mediates light-dependent fluctuation of hippocampal function in a diurnal rodent
Date: 10/2021
Authors: Joel E. Soler, Hang Xiong, Faiez Samad, Fredric P. Manfredsson, Alfred J. Robison, Antonio A. Núñez, Lily Yan
Oxytocin receptors in the midbrain dorsal raphe are essential for postpartum maternal social and affective behaviors
Date: 09/2021
Authors: Zachary A. Grieb, Emma G. Ford, Mahircan Yagan, Billy Y.B. Lau, Fredric P. Manfredsson, Keerthi Krishnan, Joseph S. Lonstein
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis
Date: 08/2021
Authors: Andrea Sturchio, Alok K. Dwivedi, Christina B. Young, Tarja Malm, Luca Marsili, Jennifer S. Sharma, Abhimanyu Mahajan, Emily J. Hill, Samir El Andaloussi, Kathleen L. Poston, Fredric P. Manfredsson, Lon S. Schneider, Kariem Ezzat, Alberto J. Espay
Fredric Manfredsson, PhD
Gene Therapy, Parkinson's
Fredric Manfredsson, PhD, is an associate professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Manfredsson’s expertise includes microbiology and virology, with a special interest in gene therapy for Parkinson’s disease and other neurodegenerative diseases. He is a member of the American Society for Gene & Cell Therapy, The American Society for Neural Therapy and Repair, and the Society for Neuroscience.
Dr. Manfredsson earned his doctorate degree in neuroscience from the University of Florida in Gainesville, where he also completed a postdoctoral fellowship in neuroscience.
Dr. Manfredsson’s research has multiple focuses. One aspect is to better understand the role of the protein alpha-synuclein in both healthy cells and those affected by Parkinson’s disease. His research also emphasizes understanding the symptomology of the disease, with a focus on the treatment of levodopa-induced dyskinesia and nonmotor symptoms experienced by nearly all patients with Parkinson’s disease.
- Postdoctoral Fellowship, University of Florida, Department of Neuroscience, 2006-2010
- PhD, University of Florida, Graduate Program in Biomedical Sciences, Neuroscience, 2006
- BS, Arizona State University, Microbiology, 1999
- President, American Society for Neural Therapy and Repair, 2018-2020
- Fellow, American Society for Neural Therapy and Repair, 2015-Present
- Cover Image, Molecular Therapy, June 2009, March 2015
- Julius Axelrod Travel Award, Society for Neuroscience, 2011
- Alumni Fellowship, University of Florida, 2001-2005
- American Society for Gene & Cell Therapy
- The American Society for Neural Therapy and Repair
- Society for Neuroscience
2021 Workshop: Neurodegenerative Diseases in the Gut-Brain Axis - Parkinson's Disease
Date: 02/2022
Authors: Gary M. Mawe, Kirsteen N. Browning, Fredric P. Manfredsson, Michael Camilleri, Frank A. Hamilton, Jonathan A. Hollander, Beth-Anne Sieber, Patricia Greenwel, Terez Shea-Donohue, John W. Wiley
Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease
Date: 12/2021
Authors: Juozas Gordevicius, Peipei Li, Lee L. Marshall, Bryan A. Killinger, Sean Lang, Elizabeth Ensink, Nathan C. Kuhn, Wei Cui, Nazia Maroof, Roberta Lauria, Christina Rueb, Juliane Siebourg-Polster, Pierre Maliver, Jared Lamp, Irving Vega, Fredric P. Manfredsson, Markus Britschgi, Viviane Labrie
Orexin (hypocretin) mediates light-dependent fluctuation of hippocampal function in a diurnal rodent
Date: 10/2021
Authors: Joel E. Soler, Hang Xiong, Faiez Samad, Fredric P. Manfredsson, Alfred J. Robison, Antonio A. Núñez, Lily Yan
Oxytocin receptors in the midbrain dorsal raphe are essential for postpartum maternal social and affective behaviors
Date: 09/2021
Authors: Zachary A. Grieb, Emma G. Ford, Mahircan Yagan, Billy Y.B. Lau, Fredric P. Manfredsson, Keerthi Krishnan, Joseph S. Lonstein
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis
Date: 08/2021
Authors: Andrea Sturchio, Alok K. Dwivedi, Christina B. Young, Tarja Malm, Luca Marsili, Jennifer S. Sharma, Abhimanyu Mahajan, Emily J. Hill, Samir El Andaloussi, Kathleen L. Poston, Fredric P. Manfredsson, Lon S. Schneider, Kariem Ezzat, Alberto J. Espay