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Barrow-ASU Center for Preclinical Imaging

Focus and Mission

The mission of the Barrow-ASU Center for Preclinical Imaging is to provide state-of-the-art imaging technology and expertise for researchers in the Phoenix area. Our center provides a wide array of imaging modalities including MRI, bioluminescence and florescence, microPET, and microCT.

The Center is a joint effort between Barrow Neurological Institute and Arizona State University. Together, our goal is to provide essential core technologies to Valley researchers and, as a result, advance biosciences across the entire State of Arizona.

Over the past several decades, advances in imaging science have unlocked new discoveries in biology and medicine. Our facility makes this advanced technology available to researchers across Central Arizona. Using these resources, investigators can examine the in vivo anatomy and function of their preclinical models.

In addition to advanced technology, the Center for Preclinical Imaging also offers professional expertise to help researchers develop and implement their imaging protocols.

Virtual Tour

Ashley Stokes, PhD
Ashley M. Stokes, PhD
Assistant Professor, Neuroimaging Research

Novel experimental model of brain arteriovenous malformations using conditional Alk1 gene deletion in transgenic mice

By Chul Han, Michael J Lang, Candice L Nguyen, Ernesto Luna Melendez, Shwetal Mehta, Gregory H Turner, Michael T Lawton, S Paul Oh

Published in Journal of Neurosurgery

Hereditary hemorrhagic telangiectasia is the only condition associated with multiple inherited brain arteriovenous malformations (AVMs). Therefore, a model was developed with a genetics-based approach that conditionally deleted the causative activin receptor-like kinase 1 (Acvrl1 or Alk1) gene. Radiographic and histopathological findings were correlated, and AVM stability and hemorrhagic behavior over time were examined.

Image Courtesy of Journal of Neurosurgery

How can we help you?

Ashley Stokes, PhD
Program Director, Preclinical Imaging
Barrow Neurological Institute
St. Joseph’s Hospital and Medical Center

Core Staff Members

Ashley Stokes, PhD
Program Director, Barrow Neurological Institute
Phone: (602) 406-8789

Alberto Fuentes
Research Engineer II
Phone: (602) 406-5595

Affiliated Researchers

Vikram Kodibagkar, PhD
Associate Professor, Arizona State University

Arizona State University
In collaboration with Arizona State University