Faculty & Staff Directory
Lauren Gittings, PhD
Lauren Gittings, PhD, is a postdoctoral research fellow in the Sattler Laboratory within the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Gittings’ expertise is in the research of neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Dr. Gittings received her doctorate in neurodegenerative diseases from University College London in the United Kingdom.
Dr. Gittings’ research involves using cell models and patient tissue to identify mechanisms of disease pathogenesis in the ALS/FTD disease spectrum. This involves investigating the role of splicing variants and their effect on synaptic dysfunction and cortical degeneration, as well as identifying cellular and molecular signatures that influence cognitive impairment in ALS.
- PhD, University College London, 2018
- BSc, University of Bath, Natural Sciences, 2014
- Poster Prize Winner, Live Like Lou Symposium, Phoenix, 2022
- Student Travel Award, University of College London Doctoral School, 2018
Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
Date: 01/2023
Authors: Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system
Date: 02/2021
Authors: Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, Linda Partridge
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis
Date: 11/2020
Authors: Alexander Bampton, Lauren M. Gittings, Pietro Fratta, Tammaryn Lashley, Ariana Gatt
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity
Date: 02/2020
Authors: Lauren M. Gittings, Steven Boeynaems, Daniel Lightwood, Alison Clargo, Sarfaraj Topia, Lisa Nakayama, Claire Troakes, David M. Mann, Aaron D. Gitler, Tammaryn Lashley, Adrian M. Isaacs
Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
Date: 01/2020
Authors: Lauren M. Gittings, Rita Sattler
Lauren Gittings, PhD
Lauren Gittings, PhD, is a postdoctoral research fellow in the Sattler Laboratory within the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Gittings’ expertise is in the research of neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Dr. Gittings received her doctorate in neurodegenerative diseases from University College London in the United Kingdom.
Dr. Gittings’ research involves using cell models and patient tissue to identify mechanisms of disease pathogenesis in the ALS/FTD disease spectrum. This involves investigating the role of splicing variants and their effect on synaptic dysfunction and cortical degeneration, as well as identifying cellular and molecular signatures that influence cognitive impairment in ALS.
- PhD, University College London, 2018
- BSc, University of Bath, Natural Sciences, 2014
- Poster Prize Winner, Live Like Lou Symposium, Phoenix, 2022
- Student Travel Award, University of College London Doctoral School, 2018
Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
Date: 01/2023
Authors: Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system
Date: 02/2021
Authors: Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, Linda Partridge
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis
Date: 11/2020
Authors: Alexander Bampton, Lauren M. Gittings, Pietro Fratta, Tammaryn Lashley, Ariana Gatt
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity
Date: 02/2020
Authors: Lauren M. Gittings, Steven Boeynaems, Daniel Lightwood, Alison Clargo, Sarfaraj Topia, Lisa Nakayama, Claire Troakes, David M. Mann, Aaron D. Gitler, Tammaryn Lashley, Adrian M. Isaacs
Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
Date: 01/2020
Authors: Lauren M. Gittings, Rita Sattler