iPSCs in Lewy Body Dementia (LBD)

Purpose

To isolate peripheral blood mononuclear cells (PBMCs), generate induced pluripotent stem cells (iPSCs), and examine phenotypes of Lewy Body Dementia (LBD) patient derived iPSC-neurons.

Who can participate

LBD Group

• Clinical diagnosis of Parkinson’s disease with dementia (PDD) or dementia with Lewy Bodies (DLB).

All Other Participants

• Willing and able to provide informed consent in writing or electronically and must have capacity to participate or provide assent and an appropriate LAR for duration of the study.
• Able to perform study activities
• Male or female age 18 or older.

Visits

This study requires a one time blood draw of ~40 ml.