Faculty & Staff Directory
Sandra Mihaljevic, PhD
Sandra Mihaljevic, PhD, MSc, is a postdoctoral research fellow in the Jha Laboratory within the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Mihaljevic’s expertise is in the study of brain barriers, with her doctoral research work focused on the role of the blood-cerebrospinal fluid barrier (BSCFB) in tau-induced neurodegeneration. She has developed an in vitro barrier model for tau transport and immune cell trafficking studies. Additionally, she has studied BCSFB changes at the structural and ultrastructural levels using electron microscopy, and implemented magnetic resonance imaging (MRI) for the evaluation of disease progression for mouse models of tauopathy.
Dr. Mihaljevic earned her doctorate degree from the Institute of Neuroimmunology of the Slovak Academy of Sciences in Bratislava, Slovakia and a master’s degree in experimental biology from the University of Zagreb in Croatia. While working toward her PhD, she completed a research internship at the Theodor Kocher Institute of the University of Bern in Switzerland.
Dr. Mihaljevic’s current research interests include acute brain injury conditions, particularly single-cell profiling of immunological responses in patients with these conditions. She also investigates biomarkers for improving diagnostic accuracy and for supporting the development of individualized therapeutic approaches.
- PhD, Slovak Academy of Sciences, Institute of Neuroimmunology, Neuroscience, 2022
- Internship, University of Bern, Theodor Kocher Institute, 2018-2019
- MSc, University of Zagreb, Experimental Biology (Physiology and Immunology), 2008
- BS, University of Zagreb, Biology, 2005
- Awardee, National Scholarship Program of Slovak Republic, 2018
Cerebrospinal Fluid Biomarkers for Diagnosis and the Prognostication of Acute Ischemic Stroke: A Systematic Review
Date: 06/2023
Authors: Anant Naik, Olufunmilola Adeleye, Stefan W. Koester, Ethan A. Winkler, Joelle N. Hartke, Katherine Karahalios, Sandra Mihaljevic, Anupama Rani, Sudhanshu Raikwar, Jarrod D. Rulney, Shashvat M. Desai, Lea Scherschinski, Andrew F. Ducruet, Felipe C. Albuquerque, Michael T. Lawton, Joshua S. Catapano, Ashutosh P. Jadhav, Ruchira M. Jha
Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury
Date: 02/2023
Authors: Benjamin E. Zusman, Yijen Wu, Patrick M. Kochanek, Vincent E. Vagni, Keri Janesko-Feldman, Volodymyr Gerzanich, J Marc Simard, Katherine Karahalios, D. G. Karahalios, Sandra Mihaljevic, Sudhanshu Raikwar, Anupama Rani, Jarrod Rulney, Shashvat M. Desai, Joshua Catapano, Joshua S. Catapano, Ruchira M. Jha, Ruchira Menka Jha
Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review
Date: 11/2021
Authors: Ruchira M. Jha, Ruchira Menka Jha, Anupama Rani, Shashvat M. Desai, Sudhanshu Raikwar, Sandra Mihaljevic, Amanda Munoz-Casabella, Patrick M. Kochanek, Joshua Catapano, Joshua S. Catapano, Ethan Winkler, Giuseppe Citerio, J Claude Hemphill, W Taylor Kimberly, Raj Narayan, Juan Sahuquillo, Kevin N. Sheth, J Marc Simard
Emerging therapeutic targets for cerebral edema
Date: 11/2021
Authors: Ruchira M. Jha, Ruchira Menka Jha, Sudhanshu P. Raikwar, Sandra Mihaljevic, Amanda M. Casabella, Joshua S. Catapano, Anupama Rani, Shashvat Desai, Volodymyr Gerzanich, J Marc Simard
Pathophysiology of the choroid plexus in brain diseases
Date: 11/2021
Authors: Sandra Mihaljevic, Alena Michalicova, Mangesh Bhide, Andrej Kovac
Sandra Mihaljevic, PhD
Sandra Mihaljevic, PhD, MSc, is a postdoctoral research fellow in the Jha Laboratory within the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Mihaljevic’s expertise is in the study of brain barriers, with her doctoral research work focused on the role of the blood-cerebrospinal fluid barrier (BSCFB) in tau-induced neurodegeneration. She has developed an in vitro barrier model for tau transport and immune cell trafficking studies. Additionally, she has studied BCSFB changes at the structural and ultrastructural levels using electron microscopy, and implemented magnetic resonance imaging (MRI) for the evaluation of disease progression for mouse models of tauopathy.
Dr. Mihaljevic earned her doctorate degree from the Institute of Neuroimmunology of the Slovak Academy of Sciences in Bratislava, Slovakia and a master’s degree in experimental biology from the University of Zagreb in Croatia. While working toward her PhD, she completed a research internship at the Theodor Kocher Institute of the University of Bern in Switzerland.
Dr. Mihaljevic’s current research interests include acute brain injury conditions, particularly single-cell profiling of immunological responses in patients with these conditions. She also investigates biomarkers for improving diagnostic accuracy and for supporting the development of individualized therapeutic approaches.
- PhD, Slovak Academy of Sciences, Institute of Neuroimmunology, Neuroscience, 2022
- Internship, University of Bern, Theodor Kocher Institute, 2018-2019
- MSc, University of Zagreb, Experimental Biology (Physiology and Immunology), 2008
- BS, University of Zagreb, Biology, 2005
- Awardee, National Scholarship Program of Slovak Republic, 2018
Cerebrospinal Fluid Biomarkers for Diagnosis and the Prognostication of Acute Ischemic Stroke: A Systematic Review
Date: 06/2023
Authors: Anant Naik, Olufunmilola Adeleye, Stefan W. Koester, Ethan A. Winkler, Joelle N. Hartke, Katherine Karahalios, Sandra Mihaljevic, Anupama Rani, Sudhanshu Raikwar, Jarrod D. Rulney, Shashvat M. Desai, Lea Scherschinski, Andrew F. Ducruet, Felipe C. Albuquerque, Michael T. Lawton, Joshua S. Catapano, Ashutosh P. Jadhav, Ruchira M. Jha
Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury
Date: 02/2023
Authors: Benjamin E. Zusman, Yijen Wu, Patrick M. Kochanek, Vincent E. Vagni, Keri Janesko-Feldman, Volodymyr Gerzanich, J Marc Simard, Katherine Karahalios, D. G. Karahalios, Sandra Mihaljevic, Sudhanshu Raikwar, Anupama Rani, Jarrod Rulney, Shashvat M. Desai, Joshua Catapano, Joshua S. Catapano, Ruchira M. Jha, Ruchira Menka Jha
Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review
Date: 11/2021
Authors: Ruchira M. Jha, Ruchira Menka Jha, Anupama Rani, Shashvat M. Desai, Sudhanshu Raikwar, Sandra Mihaljevic, Amanda Munoz-Casabella, Patrick M. Kochanek, Joshua Catapano, Joshua S. Catapano, Ethan Winkler, Giuseppe Citerio, J Claude Hemphill, W Taylor Kimberly, Raj Narayan, Juan Sahuquillo, Kevin N. Sheth, J Marc Simard
Emerging therapeutic targets for cerebral edema
Date: 11/2021
Authors: Ruchira M. Jha, Ruchira Menka Jha, Sudhanshu P. Raikwar, Sandra Mihaljevic, Amanda M. Casabella, Joshua S. Catapano, Anupama Rani, Shashvat Desai, Volodymyr Gerzanich, J Marc Simard
Pathophysiology of the choroid plexus in brain diseases
Date: 11/2021
Authors: Sandra Mihaljevic, Alena Michalicova, Mangesh Bhide, Andrej Kovac