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Sylvia Perez, PhD
Tau, Splicing, Dementia
Sylvia Perez, PhD, is an associate professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Perez’s expertise includes comparative neuroanatomy, with a focus on the biochemistry and connectivity of the cholinergic basal forebrain systems as well as on β-amyloid and tau pathology in Alzheimer’s disease, Down syndrome, and chronic traumatic encephalopathy. She is a member of the Society for Neuroscience.
Dr. Perez received her PhD in neuroanatomy from the University of Santiago de Compostela. She completed postdoctoral fellowships in neuroanatomy at the University of A Coruña and at the Consellería de Educación e Ciencias da Xunta de Galicia and in neurobiology at Rush University Medical Center.
Dr. Perez’s research interests include the neurobiology of the prodromal stage of Alzheimer’s disease and mild cognitive impairment. She also studies the role of tau in Down syndrome and dementia and the role of alpha-synuclein in the neurodegeneration of the cholinergic basal forebrain in Parkinson’s disease.
- Postdoctoral Fellowship, Rush University Medical Center, Department of Neurological Sciences, Neurobiology, 2002-2004
- Postdoctoral Fellowship, Rush University Medical Center, Department of Neurological Sciences, Neurobiology, 2000-2001
- Postdoctoral Fellowship, University of A Coruña, Neuroanatomy, 2000
- Postdoctoral Fellowship, Consellería de Educación e Ciencias da Xunta de Galicia, Neuroanatomy, 2000
- PhD, University of Santiago de Compostela, Neuroanatomy, 1998
- Predoctoral Fellowship, University of Santiago de Compostela, Neuroanatomy, 1995-1996
- Licentiate in Biology, University of Santiago de Compostela, Fundamental Biology, 1992
- Society for Neuroscience
- Arizona Alzheimer’s Disease Consortium at Barrow Neurological Institute Award, “Cortical tau pathologic signature: A biomarker for Down syndrome with and without dementia,” 2018-2019
- Arizona Alzheimer’s Disease Consortium at Barrow Neurological Institute Award, “Epigenetic dysregulation in cholinergic neurons in PD dementia,” 2016-2017
- Brinson Foundation Award, 2014-2015
- Rush University Research Council Pilot Award, 2009-2010
- Rush Department of Neurological Sciences Pilot Award, “Beta-amyloid induces cholinergic striatal dysfunction in a transgenic mouse model of Alzheimer’s disease.”
- Extraordinary Award for Doctoral Thesis, University of Santiago de Compostela, Biology Faculty, 1998
International Hackathon as a Tool to Augment Education, Collaboration, and Innovation in Global Neurosurgery
Date: 08/2024
Authors: Shahaan S. Razak, Timothy R. West, Sasha Tunsiricharoengul, Aparna Nair-Kanneganti, Nicole A. Perez, Mercy H. Mazurek, Zsombor Gal, Julia B. Duvall, Grant H. Rigney, Ivo H. Cerda, Mary M. Morcos, Emma Keay, Alejandra Silva Hernández, Michael T. Lawton, Brian V. Nahed, Alfredo Quiñones-Hinojosa
ChatGPT vs. web search for patient questions: what does ChatGPT do better?
Date: 06/2024
Authors: Sarek A. Shen, Carlos A. Perez-Heydrich, Deborah X. Xie, Jason C. Nellis
Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings.
Date: 05/2024
Authors: Ann-Charlotte E Granholm, Elisabet Englund, Anah Gilmore, Elizabeth Head, William H Yong, S E Pérez, Samuel J Guzman, Eric D Hamlett, Elliott J Mufson
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
Date: 05/2024
Authors: Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, S E Pérez, Bin He, Stephen D Ginsberg, Michael Mullan, Elliott J Mufson, Fiona Crawford, Joseph Ojo
Exosomes in Vascular/Neurological Disorders and the Road Ahead
Date: 04/2024
Authors: Faisal A. Alzahrani, Yasir M. Riza, Thamir M. Eid, Reema Almotairi, Lea Scherschinski, Jessica Contreras, Muhammed Nadeem, Sylvia E. Perez, Sudhanshu P. Raikwar, Ruchira M. Jha, Mark C. Preul, Andrew F. Ducruet, Michael T. Lawton, Kanchan Bhatia, Naseem Akhter, Saif Ahmad
Sylvia Perez, PhD
Tau, Splicing, Dementia
Sylvia Perez, PhD, is an associate professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Perez’s expertise includes comparative neuroanatomy, with a focus on the biochemistry and connectivity of the cholinergic basal forebrain systems as well as on β-amyloid and tau pathology in Alzheimer’s disease, Down syndrome, and chronic traumatic encephalopathy. She is a member of the Society for Neuroscience.
Dr. Perez received her PhD in neuroanatomy from the University of Santiago de Compostela. She completed postdoctoral fellowships in neuroanatomy at the University of A Coruña and at the Consellería de Educación e Ciencias da Xunta de Galicia and in neurobiology at Rush University Medical Center.
Dr. Perez’s research interests include the neurobiology of the prodromal stage of Alzheimer’s disease and mild cognitive impairment. She also studies the role of tau in Down syndrome and dementia and the role of alpha-synuclein in the neurodegeneration of the cholinergic basal forebrain in Parkinson’s disease.
- Postdoctoral Fellowship, Rush University Medical Center, Department of Neurological Sciences, Neurobiology, 2002-2004
- Postdoctoral Fellowship, Rush University Medical Center, Department of Neurological Sciences, Neurobiology, 2000-2001
- Postdoctoral Fellowship, University of A Coruña, Neuroanatomy, 2000
- Postdoctoral Fellowship, Consellería de Educación e Ciencias da Xunta de Galicia, Neuroanatomy, 2000
- PhD, University of Santiago de Compostela, Neuroanatomy, 1998
- Predoctoral Fellowship, University of Santiago de Compostela, Neuroanatomy, 1995-1996
- Licentiate in Biology, University of Santiago de Compostela, Fundamental Biology, 1992
- Society for Neuroscience
- Arizona Alzheimer’s Disease Consortium at Barrow Neurological Institute Award, “Cortical tau pathologic signature: A biomarker for Down syndrome with and without dementia,” 2018-2019
- Arizona Alzheimer’s Disease Consortium at Barrow Neurological Institute Award, “Epigenetic dysregulation in cholinergic neurons in PD dementia,” 2016-2017
- Brinson Foundation Award, 2014-2015
- Rush University Research Council Pilot Award, 2009-2010
- Rush Department of Neurological Sciences Pilot Award, “Beta-amyloid induces cholinergic striatal dysfunction in a transgenic mouse model of Alzheimer’s disease.”
- Extraordinary Award for Doctoral Thesis, University of Santiago de Compostela, Biology Faculty, 1998
International Hackathon as a Tool to Augment Education, Collaboration, and Innovation in Global Neurosurgery
Date: 08/2024
Authors: Shahaan S. Razak, Timothy R. West, Sasha Tunsiricharoengul, Aparna Nair-Kanneganti, Nicole A. Perez, Mercy H. Mazurek, Zsombor Gal, Julia B. Duvall, Grant H. Rigney, Ivo H. Cerda, Mary M. Morcos, Emma Keay, Alejandra Silva Hernández, Michael T. Lawton, Brian V. Nahed, Alfredo Quiñones-Hinojosa
ChatGPT vs. web search for patient questions: what does ChatGPT do better?
Date: 06/2024
Authors: Sarek A. Shen, Carlos A. Perez-Heydrich, Deborah X. Xie, Jason C. Nellis
Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings.
Date: 05/2024
Authors: Ann-Charlotte E Granholm, Elisabet Englund, Anah Gilmore, Elizabeth Head, William H Yong, S E Pérez, Samuel J Guzman, Eric D Hamlett, Elliott J Mufson
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
Date: 05/2024
Authors: Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, S E Pérez, Bin He, Stephen D Ginsberg, Michael Mullan, Elliott J Mufson, Fiona Crawford, Joseph Ojo
Exosomes in Vascular/Neurological Disorders and the Road Ahead
Date: 04/2024
Authors: Faisal A. Alzahrani, Yasir M. Riza, Thamir M. Eid, Reema Almotairi, Lea Scherschinski, Jessica Contreras, Muhammed Nadeem, Sylvia E. Perez, Sudhanshu P. Raikwar, Ruchira M. Jha, Mark C. Preul, Andrew F. Ducruet, Michael T. Lawton, Kanchan Bhatia, Naseem Akhter, Saif Ahmad