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  • photo of phoenix neurosurgeon Andrew Little

    Request an Appointment with Dr. Little

    Call (602) 406-3181

    Andrew S. Little, MD

    Neurosurgeon (602) 406-3181

    Andrew Little, MD, is a neurosurgeon and the director of the Pituitary Center and the Skull Base Program at Barrow Neurological Institute. He is board certified by the American Board of Neurological Surgery and an international leader in pituitary and brain tumor surgery.

    Dr. Little specializes in the treatment of pituitary tumors and other brain tumors and conditions, including trigeminal neuralgia, colloid cysts, and Chiari malformations. He performs more minimally invasive endoscopic transsphenoidal surgery than any other surgeon in the Southwest. He is a member of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons.

    Dr. Little earned his medical degree from the University of California—Irvine. He completed his residency in neurosurgery at Barrow Neurological Institute and a fellowship in minimally invasive surgery and neuroendoscopy at the Prince of Wales Private Hospital in Sydney, Australia.

    Dr. Little directs an active clinical research program focused on improving care for patients with pituitary and related tumors. His research interests include patient outcomes, quality of life, and minimally invasive surgery techniques. His philosophy of care emphasizes compassion, consideration of patient goals in the treatment planning process, and teamwork among experts inside and outside of Barrow to create a tailored treatment plan that addresses your specific needs.

    Please call (602) 406-3181 to request an appointment with Dr. Little.

    Insurance Accepted
    Education & Training
    • Fellowship, Minimally Invasive and Endoscopic Neurosurgery, Prince of Wales Private Hospital, Sydney, Australia, 2008-2009
    • Fellowship, Complex Spine Surgery, Barrow Neurological Institute, 2007-2008
    • Neurosurgical Residency, Barrow Neurological Institute, 2003-2010
    • MD, University of California – Irvine College of Medicine, 2003
    • BS, Yale University, Biochemistry and Biophysics, 1995
    Professional Memberships
    • Congress of Neurological Surgeons
    • American Association of Neurological Surgeons
    • Ad hoc reviewer: Neurosurgery, Child’s Nervous System
    Honors and Awards
    • John Green Award, Arizona Neurosurgical Society
    • Alpha Omega Alpha Honor Medical Society, University of California – Irvine College of Medicine
    • Magna cum laude, Yale University
    • Honors in major, Yale University
    Selected Publications
    1. Little AS, White WL. Short-duration, single-agent antibiotic prophylaxis for meningitis in trans-sphenoidal surgery. Pituitary. Feb 24 2011.
    2. Wait SD, Garrett MP, Little AS, Killory BD, White WL. Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts. Neurosurgery. Sep 2010;67(3):837-843; discussion 843.
    3. Little AS, Zabramski JM, Nakaji P. Simplified aqueductal stenting for isolated fourth ventricle using a small-caliber flexible endoscope in a patient with neurococcidiomycosis: technical case report. Neurosurgery. Jun 2010;66(6 Suppl Operative):373-374; discussion 374.
    4. Little AS, White WL. Prophylactic antibiotic trends in transsphenoidal surgery for pituitary lesions. Pituitary. Aug 31 2010.
    5. Little AS, Liu S, Beeman S, Sankar T, Preul MC, Hu LS, Smith KA, Baxter LC. Brain retraction and thickness of cerebral neocortex: an automated technique for detecting retraction-induced anatomic changes using magnetic resonance imaging.Neurosurgery. Sep 2010;67(3 Suppl Operative):ons277-282; discussion ons282.
    6. Little AS, Smith KA, Kirlin K, Baxter LC, Chung S, Maganti R, Treiman DM. Modifications to the subtemporal selective amygdalohippocampectomy using a minimal-access technique: seizure and neuropsychological outcomes. J Neurosurg. Dec 2009;111(6):1263-1274.
    7. Little AS, Shetter AG, Shetter ME, Kakarla UK, Rogers CL. Salvage gamma knife stereotactic radiosurgery for surgically refractory trigeminal neuralgia. Int J Radiat Oncol Biol Phys. Jun 1 2009;74(2):522-527.
    8. Little AS, Shetter AG, Shetter ME, Bay C, Rogers CL. Long-term pain response and quality of life in patients with typical trigeminal neuralgia treated with gamma knife stereotactic radiosurgery. Neurosurgery. Nov 2008;63(5):915-923; discussion 923-914.
    9. Little AS, Jittapiromsak P, Crawford NR, Deshmukh P, Preul MC, Spetzler RF, Bambakidis NC. Quantitative analysis of exposure of staged orbitozygomatic and retrosigmoid craniotomies for lesions of the clivus with supratentorial extension.Neurosurgery. May 2008;62(5 Suppl 2):ONS318-323; discussion ONS323-314.

    About Barrow Neurological Institute
    Since our doors opened as a regional specialty center in 1962, we have grown into one of the premier destinations in the world for neurology and neurosurgery. Our experienced, highly skilled, and comprehensive team of neurological specialists can provide you with a complete spectrum of care–from diagnosis through outpatient neurorehabilitation–under one roof. Barrow Neurological Institute: Discover. Educate. Heal.