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Robert Bowser, PhD
Chairman, Neurobiology,
Professor, Neurology and Neurobiology
Dr. Robert Bowser is an internationally-recognized leader in ALS research. He has contributed to pioneering efforts to discover and validate biomarkers for ALS. These biomarkers can be useful as diagnostic indicators of disease, predictors of disease progression, and also in determining the effectiveness of drugs in clinical trials. Dr. Bowser has extensive experience in the translation of basic science discoveries to the clinic to impact patient care.
As director of the ALS Research Center, Dr. Bowser directs research to determine the underlying mechanisms of ALS, identify new targets for drug treatment, develop improved therapies for ALS, and lead clinical research studies performed in numerous medical centers throughout North America.
Dr. Bowser is a graduate of Carnegie Mellon University and obtained his PhD from Yale University. He performed fellowship training at the Albert Einstein College of Medicine and was a faculty member at the University of Pittsburgh from 1994 to 2011, rising through the ranks to full professor. He joined the faculty at Barrow in 2011.
- Post-doctoral Fellowship, Pathology, Albert Einstein College of Medicine, 1992-1994
- PhD, Yale University, 1992
- BS, Carnegie Mellon University, 1987
- Society for Neuroscience
- American Society for Investigative Pathology
- American Association of Neuropathologists
- New York Academy of Sciences
- ALS Research Group
- International Society for Biological and Environmental Repositories
- American Association for the Advancement of Science
- World Federation of Neurology Research Group on Motor Neuron Diseases
- The Royal Society of Medicine
- IBM Big Data and Analytics Hero, 2016
- Sheila Essey Award for ALS Research, 2015
- NEALS NeuroBank Pioneer Award, 2015
- Arizona Innovation Challenge Award, 2015
- John and Betty VenDenburgh Chair of Neuromuscular Disease, 2012
- Scientific Advisory Board, Northeast Amyotrophic Lateral Sclerosis Consortium, 2011
- Guest Editor, International Journal of Molecular Sciences, 2010
- Science Council, Association Francaise contre les Myopathies, 2009 – 2011
- ALS Association “Walk to D’Feet ALS” Service Award, 2008
- University of Pittsburgh Innovator Award, 2008
- University of Pittsburgh Innovator Award, 2006
- Pittsburgh Magazine “40 under 40” Award for young people shaping the region, 2005
- ALS Association Lou Gehrig’s Challenge Award, 2004
- University of Pittsburgh Chancellor’s Distinguished Public Service Award, 2003
- ALS Association Public Service Award, 2002
Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes.
Date: 04/2020
Authors: Lucas Vu, Jiyan An, Tina Kovalik, Tania Gendron, Leonard Petrucelli, Robert Bowser
CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual.
Date: 01/2020
Authors: Yeomin Yun, Sung-Ah Hong, Ka-Kyung Kim, Daye Baek, Dongsu Lee, Ashwini M Londhe, Minhyung Lee, Jihyeon Yu, Zachary T McEachin, Gary J Bassell, Robert Bowser, Chadwick M Hales, Sung-Rae Cho, Janghwan Kim, Ae Nim Pae, Eunji Cheong, Sangwoo Kim, Nicholas M Boulis, Sangsu Bae, Yoon Ha
Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1
Date: 01/2020
Authors: David X. Medina, Eugene P Chung, Collin D Teague, Robert Bowser, Rachael W Sirianni
IL6 receptor(358)Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis.
Date: 11/2019
Authors: Marlena Wosiski-Kuhn, Mac Robinson, Jane Strupe, Phonepasong Arounleut, Matthew Martin, James Caress, Michael Cartwright, Robert Bowser, Merit Cudkowicz, Carl Langefeld, Gregory A Hawkins, Carol Milligan
Neurofilaments in pre-symptomatic ALS and the impact of genotype.
Date: 11/2019
Authors: Michael Benatar, Joanne Wuu, Vittoria Lombardi, Andreas Jeromin, Robert Bowser, Peter M Andersen, Andrea Malaspina
- English
Robert Bowser, PhD
Chairman, Neurobiology,
Professor, Neurology and Neurobiology
Dr. Robert Bowser is an internationally-recognized leader in ALS research. He has contributed to pioneering efforts to discover and validate biomarkers for ALS. These biomarkers can be useful as diagnostic indicators of disease, predictors of disease progression, and also in determining the effectiveness of drugs in clinical trials. Dr. Bowser has extensive experience in the translation of basic science discoveries to the clinic to impact patient care.
As director of the ALS Research Center, Dr. Bowser directs research to determine the underlying mechanisms of ALS, identify new targets for drug treatment, develop improved therapies for ALS, and lead clinical research studies performed in numerous medical centers throughout North America.
Dr. Bowser is a graduate of Carnegie Mellon University and obtained his PhD from Yale University. He performed fellowship training at the Albert Einstein College of Medicine and was a faculty member at the University of Pittsburgh from 1994 to 2011, rising through the ranks to full professor. He joined the faculty at Barrow in 2011.
- Post-doctoral Fellowship, Pathology, Albert Einstein College of Medicine, 1992-1994
- PhD, Yale University, 1992
- BS, Carnegie Mellon University, 1987
- Society for Neuroscience
- American Society for Investigative Pathology
- American Association of Neuropathologists
- New York Academy of Sciences
- ALS Research Group
- International Society for Biological and Environmental Repositories
- American Association for the Advancement of Science
- World Federation of Neurology Research Group on Motor Neuron Diseases
- The Royal Society of Medicine
- IBM Big Data and Analytics Hero, 2016
- Sheila Essey Award for ALS Research, 2015
- NEALS NeuroBank Pioneer Award, 2015
- Arizona Innovation Challenge Award, 2015
- John and Betty VenDenburgh Chair of Neuromuscular Disease, 2012
- Scientific Advisory Board, Northeast Amyotrophic Lateral Sclerosis Consortium, 2011
- Guest Editor, International Journal of Molecular Sciences, 2010
- Science Council, Association Francaise contre les Myopathies, 2009 – 2011
- ALS Association “Walk to D’Feet ALS” Service Award, 2008
- University of Pittsburgh Innovator Award, 2008
- University of Pittsburgh Innovator Award, 2006
- Pittsburgh Magazine “40 under 40” Award for young people shaping the region, 2005
- ALS Association Lou Gehrig’s Challenge Award, 2004
- University of Pittsburgh Chancellor’s Distinguished Public Service Award, 2003
- ALS Association Public Service Award, 2002
Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes.
Date: 04/2020
Authors: Lucas Vu, Jiyan An, Tina Kovalik, Tania Gendron, Leonard Petrucelli, Robert Bowser
CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual.
Date: 01/2020
Authors: Yeomin Yun, Sung-Ah Hong, Ka-Kyung Kim, Daye Baek, Dongsu Lee, Ashwini M Londhe, Minhyung Lee, Jihyeon Yu, Zachary T McEachin, Gary J Bassell, Robert Bowser, Chadwick M Hales, Sung-Rae Cho, Janghwan Kim, Ae Nim Pae, Eunji Cheong, Sangwoo Kim, Nicholas M Boulis, Sangsu Bae, Yoon Ha
Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1
Date: 01/2020
Authors: David X. Medina, Eugene P Chung, Collin D Teague, Robert Bowser, Rachael W Sirianni
IL6 receptor(358)Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis.
Date: 11/2019
Authors: Marlena Wosiski-Kuhn, Mac Robinson, Jane Strupe, Phonepasong Arounleut, Matthew Martin, James Caress, Michael Cartwright, Robert Bowser, Merit Cudkowicz, Carl Langefeld, Gregory A Hawkins, Carol Milligan
Neurofilaments in pre-symptomatic ALS and the impact of genotype.
Date: 11/2019
Authors: Michael Benatar, Joanne Wuu, Vittoria Lombardi, Andreas Jeromin, Robert Bowser, Peter M Andersen, Andrea Malaspina
- English