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Francisco A. Ponce, MD
- (602) 406-3181
- Fax: (833) 973-5424
The highest volume DBS surgeon
A pioneer of “asleep DBS”
Investigating surgical treatment for Alzheimer’s disease
Francisco Ponce, MD, is the Chief of Stereotactic and Functional Neurosurgery at Barrow Neurological Institute. He also serves as director of the Neurosurgery Residency Program at Barrow. He is board certified by the American Board of Neurological Surgery.
Dr. Ponce’s expertise includes deep brain stimulation (DBS) surgery for Parkinson’s disease, essential tremor, and dystonia, as well as focused ultrasound for essential tremor and tremor-dominant Parkinson’s. He is also active in the operative management of cranial and spinal trauma.
Dr. Ponce earned his medical degree from the Pritzker School of Medicine at the University of Chicago in Illinois and an undergraduate degree in physics at Harvard University in Cambridge, Massachusetts. He completed his neurosurgery residency at Barrow and a fellowship in stereotactic and functional neurosurgery at the University of Toronto in Ontario, Canada.
Dr. Ponce has published extensively on DBS and other neurosurgical procedures in peer-reviewed journals. He presents regularly at national and international conferences.
Please call (602) 406-3181 to request an appointment with Dr. Ponce.

- Aetna
- Blue Cross Blue Shield
- Cigna
- Medicare Part B
- Mercy Care at the Phoenix and Chandler Locations
- MultiPlan/AMN/RAN
- United Healthcare
- Fellowship, Stereotactic Radiosurgery, Barrow Neurological Institute
- Fellowship, Complex Spinal Neurosurgery, Barrow Neurological Institute
- Fellowship, Stereotactic and Functional Neurosurgery, University of Toronto
- Residency, Neurosurgery, Barrow Neurological Institute
- Internship, General Surgery, Banner Good Samaritan Hospital, Phoenix
- MD, University of Chicago Pritzker School of Medicine
- Graduate studies, Oxford University
- Undergraduate studies, Harvard University
Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease
Date: 11/2025
Authors: Philip A. Starr, Rajat S. Shivacharan, Edward Goldberg, Alexander I. Tröster, Paul A. House, Monique L. Giroux, Adam O. Hebb, Donald M. Whiting, Timothy A. Leichliter, Jill L. Ostrem, Leo Verhagen Metman, Sepehr Sani, Jessica A. Karl, Mustafa S. Siddiqui, Stephen B. Tatter, Ihtsham Ul Haq, Andre G. Machado, Michal Gostkowski, Michele Tagliati, Adam N. Mamelak, Michael S. Okun, Kelly D. Foote, Guillermo Moguel-Cobos, Francisco A. Ponce, Rajesh Pahwa, Kelly Lyons, Cathrin M. Buetefisch, Robert E. Gross, Corneliu C. Luca, Jonathan R. Jagid, Gonzalo J. Revuelta
Combined Dietary Restriction and Chelation Therapy Reduces Manganese Burden in SLC39A14-Associated Manganism
Date: 10/2025
Authors: Michael C. Kruer, Peter T. Skidmore, Brielle Edwards, Jennifer Heim, James Kelbert, Nathan Evans, Alex King, Patricia Cornejo, Francisco Ponce, Lisa Vanatta, Alex M. Pagnozzi, Ningning Zhao
Biomarker changes associated with fornix deep brain stimulation in Alzheimer's disease
Date: 06/2025
Authors: Jürgen Germann, Robert S. Amaral, Jennifer Tomaszczyk, Kazuaki Yamamoto, Gavin J. Elias, Flavia Venetucci Gouveia, Anna Vasilevskaya, Foad Taghdiri, Gabriel A. Devenyi, Tejas Sankar, Jeannie-Marie Leoutsakos, Cynthia A. Munro, Paul B. Rosenberg, Constantine G. Lyketsos, Esther S. Oh, William S. Anderson, Zoltan Mari, Lisa Fosdick, Kristen E. Drake, Steven D. Targum, Jo Cara Pendergrass, Anna Burke, Stephen Salloway, Wael F. Asaad, Francisco A. Ponce, Marwan Sabbagh, David A. Wolk, Gordon Baltuch, Michael S. Okun, Kelly D. Foote, Peter Giacobbe
The Effect of Exercise on Nonmotor Symptoms in Parkinson's Disease with Deep Brain Stimulation
Date: 04/2025
Authors: Sana Aslam, Chengcheng Hu, Amy W. Amara, Markey Olson, Sydney Felsen, Francisco Ponce, Holly A. Shill
Stimulation-related increases in power spectral density covary with clinical evidence of overstimulation during deep brain stimulation for pediatric dystonia
Date: 03/2025
Authors: Madelyn Pascual, Pritha Bisarad, James Kelbert, Sarah Chinander, Rose Gelineau-Morel, Carolina Gorodetsky, Angela L. Hewitt, Travis Larsh, Nicole Lucente, Jennifer O'Malley, Terrence D. Sanger, Lauren van der Werf, Jason S. Hauptman, Francisco A. Ponce, Michael C. Kruer, John A. Thompson
- English
Phoenix, AZ 85013
Appointments with Dr. Ponce are on the 2nd floor in the Barrow Brain and Spine clinic.
Complimentary valet parking is available in front of the building. Additional parking is available by entering the parking structure across 3rd Avenue.
Enter via the doors at 2910 N. 3rd Ave. beneath the Barrow Neurological Institute sign. If you park in the parking structure, take the enclosed pedestrian bridge across 3rd Avenue, then enter through the doors on the right side of the bridge.
- (602) 406-3181
- Fax: (833) 973-5424
Francisco A. Ponce, MD
- (602) 406-3181
- Fax: (833) 973-5424
The highest volume DBS surgeon
A pioneer of “asleep DBS”
Investigating surgical treatment for Alzheimer’s disease
Francisco Ponce, MD, is the Chief of Stereotactic and Functional Neurosurgery at Barrow Neurological Institute. He also serves as director of the Neurosurgery Residency Program at Barrow. He is board certified by the American Board of Neurological Surgery.
Dr. Ponce’s expertise includes deep brain stimulation (DBS) surgery for Parkinson’s disease, essential tremor, and dystonia, as well as focused ultrasound for essential tremor and tremor-dominant Parkinson’s. He is also active in the operative management of cranial and spinal trauma.
Dr. Ponce earned his medical degree from the Pritzker School of Medicine at the University of Chicago in Illinois and an undergraduate degree in physics at Harvard University in Cambridge, Massachusetts. He completed his neurosurgery residency at Barrow and a fellowship in stereotactic and functional neurosurgery at the University of Toronto in Ontario, Canada.
Dr. Ponce has published extensively on DBS and other neurosurgical procedures in peer-reviewed journals. He presents regularly at national and international conferences.
Please call (602) 406-3181 to request an appointment with Dr. Ponce.

Phoenix, AZ 85013
Appointments with Dr. Ponce are on the 2nd floor in the Barrow Brain and Spine clinic.
Complimentary valet parking is available in front of the building. Additional parking is available by entering the parking structure across 3rd Avenue.
Enter via the doors at 2910 N. 3rd Ave. beneath the Barrow Neurological Institute sign. If you park in the parking structure, take the enclosed pedestrian bridge across 3rd Avenue, then enter through the doors on the right side of the bridge.
- (602) 406-3181
- Fax: (833) 973-5424
- Aetna
- Blue Cross Blue Shield
- Cigna
- Medicare Part B
- Mercy Care at the Phoenix and Chandler Locations
- MultiPlan/AMN/RAN
- United Healthcare
- Fellowship, Stereotactic Radiosurgery, Barrow Neurological Institute
- Fellowship, Complex Spinal Neurosurgery, Barrow Neurological Institute
- Fellowship, Stereotactic and Functional Neurosurgery, University of Toronto
- Residency, Neurosurgery, Barrow Neurological Institute
- Internship, General Surgery, Banner Good Samaritan Hospital, Phoenix
- MD, University of Chicago Pritzker School of Medicine
- Graduate studies, Oxford University
- Undergraduate studies, Harvard University
Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease
Date: 11/2025
Authors: Philip A. Starr, Rajat S. Shivacharan, Edward Goldberg, Alexander I. Tröster, Paul A. House, Monique L. Giroux, Adam O. Hebb, Donald M. Whiting, Timothy A. Leichliter, Jill L. Ostrem, Leo Verhagen Metman, Sepehr Sani, Jessica A. Karl, Mustafa S. Siddiqui, Stephen B. Tatter, Ihtsham Ul Haq, Andre G. Machado, Michal Gostkowski, Michele Tagliati, Adam N. Mamelak, Michael S. Okun, Kelly D. Foote, Guillermo Moguel-Cobos, Francisco A. Ponce, Rajesh Pahwa, Kelly Lyons, Cathrin M. Buetefisch, Robert E. Gross, Corneliu C. Luca, Jonathan R. Jagid, Gonzalo J. Revuelta
Combined Dietary Restriction and Chelation Therapy Reduces Manganese Burden in SLC39A14-Associated Manganism
Date: 10/2025
Authors: Michael C. Kruer, Peter T. Skidmore, Brielle Edwards, Jennifer Heim, James Kelbert, Nathan Evans, Alex King, Patricia Cornejo, Francisco Ponce, Lisa Vanatta, Alex M. Pagnozzi, Ningning Zhao
Biomarker changes associated with fornix deep brain stimulation in Alzheimer's disease
Date: 06/2025
Authors: Jürgen Germann, Robert S. Amaral, Jennifer Tomaszczyk, Kazuaki Yamamoto, Gavin J. Elias, Flavia Venetucci Gouveia, Anna Vasilevskaya, Foad Taghdiri, Gabriel A. Devenyi, Tejas Sankar, Jeannie-Marie Leoutsakos, Cynthia A. Munro, Paul B. Rosenberg, Constantine G. Lyketsos, Esther S. Oh, William S. Anderson, Zoltan Mari, Lisa Fosdick, Kristen E. Drake, Steven D. Targum, Jo Cara Pendergrass, Anna Burke, Stephen Salloway, Wael F. Asaad, Francisco A. Ponce, Marwan Sabbagh, David A. Wolk, Gordon Baltuch, Michael S. Okun, Kelly D. Foote, Peter Giacobbe
The Effect of Exercise on Nonmotor Symptoms in Parkinson's Disease with Deep Brain Stimulation
Date: 04/2025
Authors: Sana Aslam, Chengcheng Hu, Amy W. Amara, Markey Olson, Sydney Felsen, Francisco Ponce, Holly A. Shill
Stimulation-related increases in power spectral density covary with clinical evidence of overstimulation during deep brain stimulation for pediatric dystonia
Date: 03/2025
Authors: Madelyn Pascual, Pritha Bisarad, James Kelbert, Sarah Chinander, Rose Gelineau-Morel, Carolina Gorodetsky, Angela L. Hewitt, Travis Larsh, Nicole Lucente, Jennifer O'Malley, Terrence D. Sanger, Lauren van der Werf, Jason S. Hauptman, Francisco A. Ponce, Michael C. Kruer, John A. Thompson
- English