
Engineering Treatments of the Future
Neuroscience Research at Barrow
At a Glance: Our Research and Mission
Neuroscientific research has been one of the three foundational pillars supporting the mission of Barrow Neurological Institute since our doors opened in 1962. What began as a handful of researchers and clinical trials decades ago has blossomed into a modern research powerhouse: Here, dozens of research scientists are conducting translational work in the neurosciences, hundreds of clinical and observational trials are offering hope to patients with intractable diseases, and numerous scientists and physician-scientists are working to bring the latest discoveries from the laboratory to the clinic. We’re also home to the Ivy Brain Tumor Center, the largest Phase 0 clinical trials program in the world.
Within the Department of Translational Neuroscience, Barrow scientists and physician-scientists conduct leading-edge research into neurodegenerative disease, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and Parkinson’s disease, as well as neuroimaging, traumatic brain injury, cerebrovascular diseases, and stroke. They incorporate new and cutting edge technologies to explore disease pathogenesis, as well as develop and test new therapies.
Our physician-scientists in our Department of Neurology are conducting groundbreaking research in neuro-epidemiology, uncovering previously unknown risk factors for Parkinson’s disease, ALS, and Alzheimer’s disease. Essential to this effort is the Barrow Neuro Analytics Center, where our team is bringing the computational power of supercomputers and advanced statistical analysis to bear on massive datasets to demystify the relationship between genetics, the environment, and health outcomes.
Building on our strong history of innovation in neurosurgical devices and spinal instrumentation, neuroscience research at Barrow continues to specialize and adapt as advances are made in the field.
Leading the Way
Barrow is an international leader in neuroscience research. We are a major force leading, designing, and conducting clinical trials and observational trials—paving the way for future cures.
Offering more than 287 active clinical trials
More than 1,000 patients enrolled in neuroscience clinical trials
196 peer-reviewed articles published in the most recent academic year
More than $57 million in federal research funding received in FY24

Centers, Collaborations & Consortiums
Groundbreaking technologies like AI, machine learning, and brain-computer interfaces are disrupting and accelerating how we make discoveries that will profoundly impact our patients. These efforts cross continents, bringing together the brightest minds in the neurosciences to upend the status quo and accomplish the unimaginable.

Research Programs & Laboratories
These translational programs aim to create and deliver new therapeutic agents—and hope—to people with neurological diseases. Our researchers are investigating the deepest functioning of the brain, spinal cord, and nerves to solve the most recalcitrant mysteries of the mind and body.

Core Facilities & Biobank
The next generation of therapeutics demands access to state-of-the-art technology and expertise for researchers around the world. Here in Phoenix, we deliver the advanced tools and resources to support our investigators locally and abroad.